Koch B, Simonis G, Farthmann E H
Dtsch Med Wochenschr. 1979 Nov 16;104(46):1632-4. doi: 10.1055/s-0028-1129160.
Of 339 goitres with "cold" nodules 17.7% were histologically malignant. Related to all cold nodules which were examined, this suggest a "true" malignancy rate of nodules of about 0.4%. The risk of malignancy is highest in patients over 60 years of age. The malignancy rate was high, at 23%, in cold nodules of recurrent goitres. Fine-needle aspiration biopsy pre-operatively will correctly diagnose over 90% of malignant nodules.
在339个有“冷”结节的甲状腺肿中，17.7%在组织学上为恶性。相对于所有接受检查的冷结节而言，这表明结节的“真正”恶性率约为0.4%。60岁以上患者的恶性风险最高。复发性甲状腺肿的冷结节中恶性率较高，为23%。术前细针穿刺活检能正确诊断90%以上的恶性结节。
