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两种中性聚合物对人体红细胞的几何形状和可变形性的影响。

The effects of two neutral polymers on the geometry and deformability of the human erythrocyte.

作者信息

Sewchand L S, Leuchter S, Lovlin R E, Beck J S, Rowlands S

出版信息

Experientia. 1979 Oct 15;35(10):1320-1. doi: 10.1007/BF01963983.

DOI:10.1007/BF01963983
PMID:499407
Abstract

Polyvinylpyrrolidone and dextran decrease cellular deformability. Changes in volume do not wholly account for the changes which imply a stiffening of the plasma membrane. The effects differ from those induced by charged macromolecules.

摘要

聚乙烯吡咯烷酮和右旋糖酐会降低细胞的变形能力。体积的变化并不能完全解释这些变化,这意味着质膜变硬。这些效应与带电大分子所诱导的效应不同。

相似文献

1
The effects of two neutral polymers on the geometry and deformability of the human erythrocyte.两种中性聚合物对人体红细胞的几何形状和可变形性的影响。
Experientia. 1979 Oct 15;35(10):1320-1. doi: 10.1007/BF01963983.
2
Effects of dextran and polyvinylpyrrolidone on red cell geometry and membrane elasticity.右旋糖酐和聚乙烯吡咯烷酮对红细胞形态及膜弹性的影响。
Ann N Y Acad Sci. 1983;416:255-62. doi: 10.1111/j.1749-6632.1983.tb35192.x.
3
[Comparative effect of polyvinylpyrrolidone and dextran on erythrocyte sedimentation rate in vitro. I. General aspect of the phenomenon studies on erythrocytes from different species].聚乙烯吡咯烷酮和右旋糖酐对体外红细胞沉降率的比较作用。I. 对不同物种红细胞现象研究的总体情况
Ann Pharm Fr. 1954 Jul-Aug;12(7-8):518-27.
4
Chemically sensitized erythrocytes for hemagglutination reactions.用于血凝反应的化学致敏红细胞。
J Forensic Sci. 1990 Sep;35(5):1115-24.
5
The effect of polyvinylpyrrolidone, mannitol, dextrose and of various dextrans on red blood cell charge.
Bibl Anat. 1965;7:262-6.
6
Modes of rouleaux formation of human red blood cells in polyvinylpyrrolidone and dextran solutions.
Can J Physiol Pharmacol. 1979 Nov;57(11):1213-22. doi: 10.1139/y79-183.
7
[Action of certain macro-molecular polymers with special reference to dextran and polyvinylpyrrolidone on phagocytic function of the reticulo-endothelial system].[某些大分子聚合物,特别是葡聚糖和聚乙烯吡咯烷酮对网状内皮系统吞噬功能的作用]
C R Seances Soc Biol Fil. 1956;150(2):317-21.
8
[Histamine mechanism of action of some polymers].[某些聚合物的组胺作用机制]
Acta Allergol Suppl (Copenh). 1953;3:168-9.
9
[Comparative effect of polyvinylpyrrolidone and dextran on erythrocyte sedimentation in vitro. II. Influence of the ratio of blood to colloidal solution].聚乙烯吡咯烷酮与右旋糖酐对体外红细胞沉降的比较作用。II. 血液与胶体溶液比例的影响
Ann Pharm Fr. 1954 Jul-Aug;12(7-8):528-33.
10
PVP contrasted with dextran and a multifactor theory of cryoprotection.聚乙烯吡咯烷酮与右旋糖酐及冷冻保护的多因素理论的对比。
Cryobiology. 1974 Feb;11(1):60-72. doi: 10.1016/0011-2240(74)90039-x.

本文引用的文献

1
MECHANICAL PROPERTIES OF THE RED CELL MEMBRANE. I. MEMBRANE STIFFNESS AND INTRACELLULAR PRESSURE.红细胞膜的力学性质。I. 膜硬度与细胞内压力。
Biophys J. 1964 Mar;4(2):115-35. doi: 10.1016/s0006-3495(64)86773-4.
2
[Quantitative studies on the adsorption of polyvinylpyrrolidones on erythrocyte surface. I. Experiments and results].[聚乙烯吡咯烷酮在红细胞表面吸附的定量研究。I. 实验与结果]
Blut. 1963 May;9:145-64. doi: 10.1007/BF01837805.
3
[Quantitative studies on the attachment of polyvinlpyrrolidone to the erythrocyte surface. II. Further evaluation and discussion of results of the experiment].
[聚乙烯吡咯烷酮与红细胞表面结合的定量研究。II. 实验结果的进一步评估与讨论]
Blut. 1963 Jul;9:215-37.
4
Disk-sphere transformation and plasticity alteration of red blood cells.红细胞的盘-球转化与可塑性改变
Nature. 1965 Apr 24;206(982):409-10. doi: 10.1038/206409a0.
5
The measurement of the haematocrit and flexibility of erythrocytes with a centrifuge.用离心机测量红细胞压积和红细胞柔韧性。
Biorheology. 1968 Mar;5(1):1-14. doi: 10.3233/bir-1968-5101.
6
The influence of water-soluble colloids on the mechanism of erythrocyte aggregation.水溶性胶体对红细胞聚集机制的影响。
Bibl Haematol. 1969;33:322-9. doi: 10.1159/000384853.
7
The interactions of fibrinogen and dextrans with erythrocytes.纤维蛋白原和右旋糖酐与红细胞的相互作用。
J Physiol. 1972 May;223(1):199-212. doi: 10.1113/jphysiol.1972.sp009841.
8
Decreased red cell deformability in burn patients.烧伤患者红细胞变形性降低。
Can J Surg. 1974 Jul;17(4):239-43.
9
Role of surface electric charge in red blood cell interactions.表面电荷在红细胞相互作用中的作用。
J Gen Physiol. 1973 May;61(5):638-54. doi: 10.1085/jgp.61.5.638.
10
The mode and kinetics of the human red cell doublet formation.人类红细胞双联体形成的模式与动力学
Biorheology. 1974 Jul;11(4):241-51. doi: 10.3233/bir-1974-11404.