Yamashita T, Takamori K, Tanaka Y
Experientia. 1979 Oct 15;35(10):1345-7. doi: 10.1007/BF01963999.
The modification of neutrophils with amino group blocking reagents of different chemical specificities showed that dansyl chloride caused inhibition of chemotaxis without suppression of random movement. Dansylated neutrophils, like control cells, ingested bacteria. Neither the stimulated cyanide-insensitive respiration, nor lactate production during phagocytosis, was affected significantly by dansylation as compared with the inhibition of directed movement.
用具有不同化学特异性的氨基封闭试剂对中性粒细胞进行修饰，结果表明丹磺酰氯会抑制趋化性，但不会抑制随机运动。丹磺酰化的中性粒细胞与对照细胞一样，能够吞噬细菌。与定向运动受到的抑制相比，丹磺酰化对吞噬过程中受刺激的氰化物不敏感呼吸或乳酸生成均无显著影响。
