Barham S S, Lieber M M, Veneziale C M
Invest Urol. 1979 Nov;17(3):248-56.
We have designed a topographic anatomic study using scanning electron microscopy to define surface changes in seminal vesicle epithelium during normal development and after bilateral orchiectomy. Scanning electron microscopy of seminal vesicles from 1-day, 4-week, and 3-month-old intact animals revealed a microvilli-studded luminal epithelial surface with high polyhedral cell profiles extending into the luminal area. Deep furrows outlined all intercellular junctions. Microvilli profiles ranged from short knob-like projections located preferentially along cell margins in 1-day-old animals to 1 mu-long microvilli wih random distribution in mature animals. The most striking finding was that the seminal vesicle epithelium in castrated animals did not revert to the prepubertal state. Rather, cell apices receded from the luminal surface to a level below that of the cell borders and microvilli generally remained somewhat longer in the castrate than in the prepubertal animal. These morphologic findings suggest that the seminal vesicle epithelium in the prepubertal animal and the long-term castrate are quite different.
我们设计了一项局部解剖学研究，使用扫描电子显微镜来确定精囊上皮在正常发育过程中以及双侧睾丸切除术后的表面变化。对1日龄、4周龄和3月龄完整动物的精囊进行扫描电子显微镜检查，发现管腔上皮表面布满微绒毛，高多面体形状的细胞轮廓延伸到管腔区域。深沟勾勒出所有细胞间连接。微绒毛形态从1日龄动物中优先沿细胞边缘分布的短瘤状突起，到成熟动物中随机分布的1微米长的微绒毛不等。最显著的发现是，去势动物的精囊上皮并未恢复到青春期前状态。相反，细胞顶端从管腔表面退缩到低于细胞边界的水平，并且去势动物中的微绒毛通常比青春期前动物中的微绒毛稍长。这些形态学发现表明，青春期前动物和长期去势动物的精囊上皮有很大不同。
