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小鼠中的巨噬细胞嗜细胞抗体：细菌脂多糖对小鼠腹腔细胞摄取免疫球蛋白的作用机制。

Macrophage cytophilic antibody in mice: mechanism of action of bacterial lipopolysaccharide on the uptake of immunoglobulins by mouse peritoneal cells.

作者信息

Tizard I R

出版信息

Infect Immun. 1971 Oct;4(4):402-6. doi: 10.1128/iai.4.4.402-406.1971.

DOI:10.1128/iai.4.4.402-406.1971
PMID:5005300
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC416321/
Abstract

The action of injected bacterial lipopolysaccharide upon the uptake of cytophilic antibodies by macrophages was found to be unrelated either to changes in surface charge or to the rate of anaerobic glycolysis of these cells. It is apparently mediated by alterations in the levels of material in the serum which enhances the uptake of cytophilic antibody by macrophages. This enhancing material does not appear to be an immunoglobulin nor can it be generated by the action of endotoxin on either whole blood or serum.

摘要

已发现，注射的细菌脂多糖对巨噬细胞摄取亲细胞抗体的作用，既与这些细胞表面电荷的变化无关，也与它们的无氧糖酵解速率无关。它显然是由血清中某些物质水平的改变介导的，这些物质会增强巨噬细胞对亲细胞抗体的摄取。这种增强物质似乎不是一种免疫球蛋白，内毒素对全血或血清的作用也无法产生这种物质。

相似文献

1
Macrophage cytophilic antibody in mice: mechanism of action of bacterial lipopolysaccharide on the uptake of immunoglobulins by mouse peritoneal cells.小鼠中的巨噬细胞嗜细胞抗体：细菌脂多糖对小鼠腹腔细胞摄取免疫球蛋白的作用机制。
Infect Immun. 1971 Oct;4(4):402-6. doi: 10.1128/iai.4.4.402-406.1971.
2
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引用本文的文献

1
Macrophage-cytophilic antibodies and the functions of macrophage-bound immunoglobulins.巨噬细胞嗜细胞抗体与巨噬细胞结合免疫球蛋白的功能
Bacteriol Rev. 1971 Dec;35(4):365-78. doi: 10.1128/br.35.4.365-378.1971.
2
Effect of endotoxin on tumor resistance in mice.内毒素对小鼠肿瘤抵抗力的影响。
Infect Immun. 1974 Jan;9(1):95-100. doi: 10.1128/iai.9.1.95-100.1974.

本文引用的文献

1
Macrophage cytophilic antibody in mice: effect of bacterial lipopolysaccharide on the uptake of immunoglobulins by mouse peritoneal cells.小鼠巨噬细胞亲合抗体：细菌脂多糖对小鼠腹腔细胞摄取免疫球蛋白的影响。
Infect Immun. 1971 Mar;3(3):472-7. doi: 10.1128/iai.3.3.472-477.1971.
2
INCREASE IN MACROGLOBULIN ANTIBODIES OF MOUSE AND PIG FOLLOWING INJECTION OF BACTERIAL LIPOPOLYSACCHARIDE.注射细菌脂多糖后小鼠和猪体内巨球蛋白抗体的增加。
Immunology. 1964 Jul;7(4):394-402.
3
Symposium on bacterial endotoxins. III. Metabolic effects of endotoxins on mammalian cells.细菌内毒素研讨会。III. 内毒素对哺乳动物细胞的代谢作用。
Bacteriol Rev. 1961 Dec;25(4):447-56. doi: 10.1128/br.25.4.447-456.1961.
4
An apparatus for microelectrophoresis of small particles.一种用于小颗粒微电泳的装置。
Nature. 1958 Sep 6;182(4636):642-4. doi: 10.1038/182642a0.
5
The effect of Salm. typhi and its endotoxin on the phagocytic activity of the reticuloendothelial system in mice.伤寒杆菌及其内毒素对小鼠网状内皮系统吞噬活性的影响。
Br J Exp Pathol. 1955 Jun;36(3):226-35.
6
[Effect of bacterial pyrogens (lipopolysaccharides) on phagocytic activity of granulocytes and on electric surface charging of the human blood cells in vivo].[细菌热原（脂多糖）对粒细胞吞噬活性及人体血细胞体内表面电荷的影响]
Klin Wochenschr. 1954 Jun 1;32(21-22):500-3. doi: 10.1007/BF01467091.
7
[Chemical and biological analysis of highly purified bacterial polysaccharides].[高纯度细菌多糖的化学与生物学分析]
Dtsch Med Wochenschr. 1953 May 22;78(21):17-9.
8
The release of specific bactericidal antibodies by endotoxin.内毒素释放特定的杀菌抗体。
J Exp Med. 1966 Feb 1;123(2):205-12. doi: 10.1084/jem.123.2.205.
9
Passive sensitization of tissue cells. 1. Passive sensitization of macrophages by guinea-pig cytophilic antibody.组织细胞的被动致敏。1. 豚鼠嗜细胞抗体对巨噬细胞的被动致敏。
Int Arch Allergy Appl Immunol. 1965;28(1):87-104.
10
"Lymphokines": non-antibody mediators of cellular immunity generated by lymphocyte activation.“淋巴因子”：由淋巴细胞激活产生的细胞免疫非抗体介质。
Nature. 1969 Oct 4;224(5214):38-42. doi: 10.1038/224038a0.