Harlozińska A, Zawadzka H, Woźniewski A, Richter R
Arch Immunol Ther Exp (Warsz). 1975;23(2):247-55.
Using the method of double diffusion in agar and precipitation, inhibition test and specific antitumor immune sera, perchloric extracts of carcinomas of the stomach and lower parts of the gastrointestinal tract were found to contain a carcinoembryonic antigen with electrophoretic mobility of gamma-globulins. Antigens from carcinomas of all studied parts of the gastrointestinal tract (stomach, sigmoid, colon and rectum) gave lines of identity in the test of double diffusion in agar. This antigen was not demonstrable in the mucous membranes surrounding the carcinomas of the gastrointestinal tract or in normal organs (gastrointestinal mucosa, liver, kidneys, spleen, plasma), or in perchloric extracts of gastrointestinal tissues of human fetuses.
采用琼脂双向扩散和沉淀法、抑制试验以及特异性抗肿瘤免疫血清，发现胃和胃肠道下部癌的高氯酸提取物含有一种癌胚抗原，其电泳迁移率与γ球蛋白相同。在胃肠道所有研究部位（胃、乙状结肠、结肠和直肠）癌组织中提取的抗原，在琼脂双向扩散试验中呈现同一沉淀线。在胃肠道癌周围的黏膜、正常器官（胃肠道黏膜、肝脏、肾脏、脾脏、血浆）或人胎儿胃肠道组织的高氯酸提取物中均未检测到这种抗原。
