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The effect of phenobarbital or 2-diethylaminoethyl-2,2-diphenylvalerate on the activation of cyclophosphamide in vivo.

作者信息

Field R B, Gang M, Kline I, Venditti J M, Waravdekar V S

出版信息

J Pharmacol Exp Ther. 1972 Feb;180(2):475-83.

PMID:5010684
Abstract
摘要

相似文献

1
The effect of phenobarbital or 2-diethylaminoethyl-2,2-diphenylvalerate on the activation of cyclophosphamide in vivo.苯巴比妥或2-二乙氨基乙基-2,2-二苯基戊酸酯对环磷酰胺体内活化的影响。
J Pharmacol Exp Ther. 1972 Feb;180(2):475-83.
2
Effect of microsomal enzyme modifiers on toxicity and therapeutic activity of cyclophosphamide in mice.微粒体酶修饰剂对环磷酰胺在小鼠体内毒性及治疗活性的影响。
Arch Int Pharmacodyn Ther. 1969 Aug;180(2):391-401.
3
Effects of dosage, phenobarbital, and 2-diethylaminoethyl-2,2-diphenylvalerate on the binding of cyclophosphamide and-or its metabolites to the DNA, RNA, and protein of the embryo and liver in pregnant mice.剂量、苯巴比妥和2-二乙氨基乙基-2,2-二苯基戊酸酯对环磷酰胺及其代谢产物与妊娠小鼠胚胎和肝脏的DNA、RNA及蛋白质结合的影响。
Cancer Res. 1973 Apr;33(4):664-70.
4
Effect of phenobarbital and SKF 525A on the toxicity, elimination and metabolism of cyclophosphamide in newborn mice.苯巴比妥和SKF 525A对新生小鼠中环磷酰胺毒性、消除及代谢的影响。
J Pharmacol Exp Ther. 1973 Mar;184(3):749-56.
5
The effect of phenobarbital on cyclophosphamide antitumor activity.苯巴比妥对环磷酰胺抗肿瘤活性的影响。
Cancer Res. 1976 Aug;36(8):2785-9.
6
A biochemical and pharmacological study of therapeutic synergism with 5-fluorouracil plus cyclophosphamide in murine L1210 leukemia.
Cancer Res. 1979 Apr;39(4):1396-404.
7
Effect of phenobarbital and SKF 525A on placental transfer of cyclophosphamide in mice.
J Pharmacol Exp Ther. 1971 Apr;177(1):256-62.
8
Alterations in the toxicity and antitumor activity of methyl-CCNU in mice following pretreatment with either phenobarbital or SKF 525A.在使用苯巴比妥或SKF 525A预处理后，小鼠体内甲基环己亚硝脲的毒性和抗肿瘤活性的变化。
Cancer Treat Rep. 1979 Nov-Dec;63(11-12):1901-7.
9
Effect of phenobarbital and SKF 525-A on the teratogenicity of cyclophosphamide in mice.苯巴比妥和SKF 525 - A对环磷酰胺对小鼠致畸性的影响。
Teratology. 1968 Nov;1(4):393-8. doi: 10.1002/tera.1420010406.
10
Antileukemic synergism between cyclophosphamide and an antitumor platinum compound.
Res Commun Chem Pathol Pharmacol. 1973 Sep;6(2):419-25.

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Causes and problems of nonresponse or poor response to drugs.药物无反应或反应不佳的原因及问题。
Drugs. 1996 Apr;51(4):552-70. doi: 10.2165/00003495-199651040-00004.
2
Repeated investigations of cyclophosphamide disposition in myeloma patients receiving intermittent chemotherapy.对接受间歇性化疗的骨髓瘤患者环磷酰胺处置情况的反复研究。
Br J Clin Pharmacol. 1980 Sep;10(3):281-5. doi: 10.1111/j.1365-2125.1980.tb01756.x.
3
Cimetidine enhancement of cyclophosphamide antitumour activity.西咪替丁增强环磷酰胺的抗肿瘤活性。
Br J Cancer. 1982 Jan;45(1):35-43. doi: 10.1038/bjc.1982.5.
4
Carbon tetrachloride-induced increase in the antitumor activity of cyclophosphamide in mice: a pharmacokinetic study.
Cancer Chemother Pharmacol. 1984;12(3):167-72. doi: 10.1007/BF00256539.
5
Pharmacokinetics of high-dose cyclophosphamide in patients with metastatic bronchogenic carcinoma.高剂量环磷酰胺在转移性支气管癌患者中的药代动力学
Cancer Chemother Pharmacol. 1983;11(3):196-9. doi: 10.1007/BF00254204.
6
Clinical correlates of in vitro drug sensitivities of ovarian cancer cells.卵巢癌细胞体外药敏的临床相关性
Br J Cancer. 1983 Jul;48(1):61-8. doi: 10.1038/bjc.1983.157.
7
Effects of the induction of hepatic microsomal metabolism on the toxicity of cyclophosphamide.肝微粒体代谢诱导对环磷酰胺毒性的影响。
Br J Cancer. 1985 Jan;51(1):67-75. doi: 10.1038/bjc.1985.10.
8
Pharmacokinetic drug interactions of commonly used anticancer drugs.常用抗癌药物的药代动力学药物相互作用。
Clin Pharmacokinet. 1986 May-Jun;11(3):223-35. doi: 10.2165/00003088-198611030-00004.
9
The effect of hepatic enzyme inducers on busulfan neurotoxicity and myelotoxicity.肝酶诱导剂对白消安神经毒性和骨髓毒性的影响。
Cancer Chemother Pharmacol. 1990;27(3):226-8. doi: 10.1007/BF00685717.
10
Increase in the gastrointestinal absorption and in tissue storage of cyclophosphamide in L-1210 leukaemic mice at an advanced stage of the disease.在处于疾病晚期的L-1210白血病小鼠中，环磷酰胺的胃肠道吸收和组织储存增加。
Br J Cancer. 1975 Dec;32(6):720-9. doi: 10.1038/bjc.1975.283.