Harm K, Rehpenning W, Domesle A, Voigt K D
J Clin Chem Clin Biochem. 1979 Aug;17(8):517-22.
The number of falsely positive values occurring in 12-channel analysis was determined in two groups of patients and reference individuals. It revealed that the portion of falsely positive values actually found was statistically significant beyond that calculated on the assumption of a binomial distribution. Partly distinct correlations of the parameters combined to a profile as well as clear deviations from the normal distribution have to be taken into consideration as reasons for this discrepancy between theory and reality. The results show that the application of the binomial distribution leads to statements which significantly differ from the conditions actually present.
在两组患者和参照个体中确定了12通道分析中出现的假阳性值的数量。结果显示，实际发现的假阳性值比例在统计学上显著高于基于二项分布假设所计算的比例。参数之间部分不同的相关性组合成一种特征，以及与正态分布的明显偏差，必须被视为理论与现实之间这种差异的原因。结果表明，二项分布的应用得出的结论与实际存在的情况有显著差异。
