Stewart W K, Raffle E J
Br Med J. 1972 Mar 25;1(5803):784-6. doi: 10.1136/bmj.1.5803.784.
A brown arc affecting the distal part of the fingernail-bed, just proximal to the point of separation of the nail from its bed, has been found in 12 out of 34 patients with chronic renal disease (35%) compared with an incidence of less than 2% in a series of unselected patients. It represents a distinctive form of pigmentation, possibly due to lipochromes. No decisive association could be found between the presence or absence of the pigmented nail arc and the level of impaired renal function. Nevertheless it seems that renal disease predisposes towards the development of brown nail arcs.
在34例慢性肾病患者中，有12例（35%）发现指甲床远端靠近指甲与甲床分离点处出现棕色弧形，而在一系列未经挑选的患者中，这一发生率低于2%。它代表一种独特的色素沉着形式，可能是由于脂色素所致。在有或无色素沉着指甲弧形与肾功能损害程度之间未发现决定性关联。然而，似乎肾病易引发棕色指甲弧形的出现。
