乙酰胆碱受体：大鼠膈肌神经肌肉接头处的数量与分布
Acetylcholine receptors: number and distribution at neuromuscular junctions in rat diaphragm.
作者信息
Fambrough D M, Hartzell H C
出版信息
Science. 1972 Apr 14;176(4031):189-91. doi: 10.1126/science.176.4031.189.
PMID:5014442
Abstract
The number of acetylcholine receptors per motor end plate in the rat diaphragm, measured by the binding of [(125)1]alpha-bungarotoxin, varies directly with rat size and is (4.0 +/- 0.2) x 10(7) for full-grown male rats. Autoradiographic analysis of single fibers labeled with this substance reveals that virtually all of these receptors are localized in the end plate.
摘要
通过[（125）1]α-银环蛇毒素结合法测量，大鼠膈肌中每个运动终板的乙酰胆碱受体数量与大鼠大小直接相关，成年雄性大鼠的该数量为（4.0±0.2）×10⁷ 。对用这种物质标记的单根纤维进行放射自显影分析表明，几乎所有这些受体都位于终板中。
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