猪对后圆线虫属感染的速发型超敏反应。II. 变应原的部分特性鉴定

Immediate hypersensitivity to Metastrongylus spp. infection in the pig. II. Partial characterization of the allergens.

作者信息

Barratt M E

出版信息

Immunology. 1972 Apr;22(4):615-23.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1407828/

Abstract

Saline extracts of adult spp. were fractionated by both Sephadex gel filtration and anion exchange chromatography, and the fractions tested for allergenicity both by wheal and erythema tests in infected pigs, and by P-K tests in passively sensitized pigs. It is suggested that cross reactions, so commonly found when using nematode antigens in wheal and erythema reactions, can be eliminated by suitable dilution of the allergen. It was shown that the allergenic components had a molecular weight range of 5000 to 50,000, and were eluted from DEAE cellulose with a series of buffers of differing molarity.

摘要

对成年某种寄生虫的盐提取物进行了葡聚糖凝胶过滤和阴离子交换色谱分离，并通过在感染猪身上进行风团和红斑试验以及在被动致敏猪身上进行P-K试验来检测各馏分的致敏性。研究表明，在风团和红斑反应中使用线虫抗原时常见的交叉反应，可以通过适当稀释变应原加以消除。结果显示，致敏成分的分子量范围为5000至50000，并且用一系列不同摩尔浓度的缓冲液从DEAE纤维素上洗脱下来。

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本文引用的文献

1

IMMUNOLOGICAL STUDIES ON NIPPOSTRONGYLUS BRASILIENSIS INFECTION IN THE RAT: "SELF-CURE" PHENOMENON.大鼠巴西日圆线虫感染的免疫学研究：“自愈”现象

Exp Parasitol. 1965 Jun;16:341-7. doi: 10.1016/0014-4894(65)90056-1.

2

IMMUNOLOGICAL STUDIES ON FILARIASIS. 3. ISOLATION AND PURIFICATION OF ANTIGEN FOR INTRADERMAL SKIN TEST.丝虫病的免疫学研究。3. 用于皮内皮肤试验的抗原的分离与纯化。

Jpn J Exp Med. 1965 Apr;35:125-32.

3

[A micro-method of immuno-electrophoresis].[免疫电泳的微量方法]

Int Arch Allergy Appl Immunol. 1955;7(2):103-10.

4

The molecular weight range of nematode allergens.线虫过敏原的分子量范围。

Immunology. 1967 Nov;13(5):535-7.

5

Reaginic antibodies and immunity to Nippostrongylus brasiliensis in the rat. II. Some properties of the antibodies and antigens.大鼠体内针对巴西日圆线虫的反应素抗体与免疫性。II. 抗体和抗原的一些特性。

Immunology. 1967 May;12(5):583-97.

6

Reagin-like antibodies in rats infected with the nematode parasite Nippostrongylus brasiliensis.感染巴西日圆线虫这种线虫寄生虫的大鼠体内的类反应素抗体。

Immunology. 1967 Feb;12(2):113-31.

7

Evaluation of intradermal and serologic tests for the diagnosis of hydatid disease.用于诊断包虫病的皮内试验和血清学检测评估

Am J Trop Med Hyg. 1966 Mar;15(2):172-9. doi: 10.4269/ajtmh.1966.15.172.

8

Skin sensitizing antibody in experimental infections with Metastrogylus spp. (Nematoda).在感染似圆线虫属（线虫纲）的实验中皮肤致敏抗体

Immunology. 1970 Jan;18(1):23-6.

9

Homocytotropic antibody in pigs infected with Metastrongylus spp.感染后圆线虫属的猪体内的亲同种细胞抗体

Vet Rec. 1969 Oct 4;85(14):390. doi: 10.1136/vr.85.14.390.

10

Reagin-like antibody formation in rabbits during a heterogeneous antibody response to Ascaris antigens.家兔在对蛔虫抗原产生异种抗体反应过程中类反应素抗体的形成。

Immunology. 1970 Jan;18(1):91-8.

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