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家兔在对蛔虫抗原产生异种抗体反应过程中类反应素抗体的形成。

Reagin-like antibody formation in rabbits during a heterogeneous antibody response to Ascaris antigens.

作者信息

McAninch J R, Patterson R

出版信息

Immunology. 1970 Jan;18(1):91-8.

PMID:4983522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1455519/
Abstract

A heterogeneous antibody response was observed in rabbits immunized with crude antigens or pooled active fractions prepared by gelfiltration chromatography. The development of haemagglutinating antibodies, precipitating antibodies and reagin-like (homocytotropic) antibodies was observed. The reagin-like antibodies were shown to be heat-labile, 2-mercaptoethanol sensitive and clearly different from 7S IgG antibodies when localized by Sephadex G-200 gel-filtration chromatography.

摘要

在用粗抗原或通过凝胶过滤色谱法制备的混合活性组分免疫的兔子中观察到异质性抗体反应。观察到血凝抗体、沉淀抗体和反应素样（亲同种细胞性）抗体的产生。反应素样抗体表现为热不稳定、对2-巯基乙醇敏感，并且当通过Sephadex G-200凝胶过滤色谱法定位时，与7S IgG抗体明显不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa08/1455519/b86c353e4860/immunology00372-0106-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa08/1455519/b86c353e4860/immunology00372-0106-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa08/1455519/b86c353e4860/immunology00372-0106-a.jpg

相似文献

1
Reagin-like antibody formation in rabbits during a heterogeneous antibody response to Ascaris antigens.家兔在对蛔虫抗原产生异种抗体反应过程中类反应素抗体的形成。
Immunology. 1970 Jan;18(1):91-8.
2
The enhancement of rabbit anti-BSA IgE, homocytotropic antibody production by Corynebacterium parvum strain 10387.微小棒状杆菌10387菌株对兔抗牛血清白蛋白IgE（亲同种细胞抗体）产生的增强作用。
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Hypersensitivity to ascaris antigens. VI. Physicochemical, immunochemical and biologic properties of rabbit homocytotropic antibodies produced to crude extracts.对蛔虫抗原的超敏反应。VI. 针对粗提取物产生的兔亲同种细胞抗体的物理化学、免疫化学和生物学特性。
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Guinea-pig reaginic antibody. II. Physicochemical and biological properties.豚鼠反应素抗体。II. 物理化学和生物学特性。
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引用本文的文献

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In vitro detection of homocytotropic antibody in lungworm-infected Rocky Mountain Bighorn sheep.感染肺线虫的落基山大角羊体内亲同种细胞抗体的体外检测
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2
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Immunology. 1972 Apr;22(4):615-23.

本文引用的文献

1
Immediate reactions in the skin of experimental animals provoked by antibody-antigen interaction.抗体 - 抗原相互作用引发的实验动物皮肤即时反应。
Prog Allergy. 1958;5:459-508.
2
Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells.蛋白质和抗体研究的微量方法。I. 用鞣酸和蛋白质处理的红细胞进行血凝和血凝抑制反应的程序及一般应用。
J Immunol. 1954 May;72(5):360-7.
3
Rabbit reagin-like antibodies.兔反应素样抗体。
Int Arch Allergy Appl Immunol. 1967;32(2):201-7. doi: 10.1159/000229928.
4
The molecular weight range of nematode allergens.线虫过敏原的分子量范围。
Immunology. 1967 Nov;13(5):535-7.
5
Hypersensitivity to Ascaris antigens. I. Skin-sensitizing activity of serum fractions from guinea pigs sensitized to crude extracts.对蛔虫抗原的超敏反应。I. 对粗提物致敏的豚鼠血清组分的皮肤致敏活性。
J Immunol. 1967 May;98(5):893-900.
6
Reagin-like antibodies in rats infected with the nematode parasite Nippostrongylus brasiliensis.感染巴西日圆线虫这种线虫寄生虫的大鼠体内的类反应素抗体。
Immunology. 1967 Feb;12(2):113-31.
7
Rabbit anaphylactic antibody.兔过敏抗体。
J Exp Med. 1966 May 1;123(5):935-50. doi: 10.1084/jem.123.5.935.
8
Comparisons of reaginic antibodies from three species.三种物种反应素抗体的比较。
J Immunol. 1969 Feb;102(2):466-75.
9
A unique class of rabbit immunoglobulins eliciting passive cutaneous anaphylaxis in homologous skin.
Immunochemistry. 1968 Nov;5(6):525-42. doi: 10.1016/0019-2791(68)90089-x.
10
Spectrum of ovine immunoglobulins.绵羊免疫球蛋白谱
Proc Soc Exp Biol Med. 1968 Dec;129(3):867-70. doi: 10.3181/00379727-129-33445.