[脂质过氧化物与动脉粥样硬化。缺血性心脏病患者血液中脂质过氧化产物的含量]
[Lipid peroxides and atherosclerosis. The content of lipid peroxidation products in the blood in ischemic heart disease].
作者信息
Lankin V Z, Zakirova A N, Kasatkina L V, Kotelevtseva N V, Akhmetova B Kh
出版信息
Kardiologiia. 1979 Oct;19(10):69-72.
PMID:502174
Abstract
It was established that the content of primary (acylhydroperoxide) and secondary (intermollecular "seams" in aminophospholipids) products of lipid peroxide oxidation in blood of patients with ischemic heart disease is increased against the background of hyperlipidemia and hypercholesterolemia. It is suggested that intensification of lipid peroxide oxidation may play a role in the pathogenesis of atherosclerosis.
摘要
已确定，在高脂血症和高胆固醇血症背景下，缺血性心脏病患者血液中脂质过氧化氧化的初级产物（酰基过氧化氢）和次级产物（氨基磷脂中的分子间“接缝”）含量增加。有人认为，脂质过氧化氧化的加剧可能在动脉粥样硬化的发病机制中起作用。
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