Shapiro M J, Rickert R R
Otolaryngol Head Neck Surg (1979). 1979 Sep-Oct;87(5):653-8. doi: 10.1177/019459987908700521.
A malignant parapharyngeal neurilemmoma developed in a 45-year-old woman who had had a benign solitary neurilemmoma removed from the same area nine years previously. Incomplete excision was achieved through a mandibulotomy approach. Malignant schwannoma usually is associated with neurofibromatosis and has a poor prognosis, spreading along the nerve of origin or by blood stream. Small localized tumors should be treated aggressively by surgery. The possibility that a previously benign schwannoma underwent malignant transformation must be considered.
一名45岁女性发生了恶性咽旁神经鞘瘤,9年前她曾在同一部位切除过一个良性孤立性神经鞘瘤。通过下颌骨切开术进行了不完全切除。恶性神经鞘瘤通常与神经纤维瘤病相关,预后较差,可沿起源神经或通过血流扩散。小的局限性肿瘤应积极进行手术治疗。必须考虑先前良性神经鞘瘤发生恶性转化的可能性。