夸休可尔症患儿的硝基蓝四氮唑试验及对该试验中乳胶颗粒使用的评论
Nitro blue tetrazolium test in children with kwashiorkor with a comment on the use of latex particles in the test.
作者信息
Shousha S, Kamel K
出版信息
J Clin Pathol. 1972 Jun;25(6):494-7. doi: 10.1136/jcp.25.6.494.
Abstract
The nitro blue tetrazolium test was applied on neutrophils from children with kwashiorkor and from control children. The percentage of formazan cells formed in the kwashiorkor patients was significantly less than in the control group in spite of the presence of associated infections in the former. A direct correlation exists between the percentage of formazan cell formation and total serum proteins, albumin, and haemoglobin. These findings may reflect a decreased bactericidal activity of neutrophils in kwashiorkor. The use of latex particles is an unnecessary technical refinement of the test.
摘要
对夸休可尔症患儿及对照儿童的中性粒细胞进行了硝基蓝四氮唑试验。尽管夸休可尔症患儿存在合并感染，但其形成甲臜细胞的百分比仍显著低于对照组。甲臜细胞形成百分比与血清总蛋白、白蛋白及血红蛋白之间存在直接相关性。这些发现可能反映了夸休可尔症患儿中性粒细胞杀菌活性降低。使用乳胶颗粒是该试验不必要的技术改进。
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Nitro blue tetrazolium test in children with kwashiorkor with a comment on the use of latex particles in the test.夸休可尔症患儿的硝基蓝四氮唑试验及对该试验中乳胶颗粒使用的评论
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本文引用的文献
1
ANTIGENIC STIMULATION IN UNDERNOURISHED CHILDREN.营养不良儿童的抗原刺激
East Afr Med J. 1965 May;42:221-32.
2
Infection and kwashiorkor.感染与夸希奥科病
J Trop Pediatr Afr Child Health. 1960 Sep;6:37-43. doi: 10.1093/oxfordjournals.tropej.a057567.
3
Interactions of nutrition and infection.营养与感染的相互作用。
Am J Med Sci. 1959 Mar;237(3):367-403.
4
Kwashiorkor.夸休可尔症
J Am Med Assoc. 1953 Dec 5;153(14):1280-5.
5
In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood.人多形核白细胞的体外杀菌能力：儿童慢性肉芽肿病中活性降低。
J Clin Invest. 1967 Apr;46(4):668-79. doi: 10.1172/JCI105568.
6
Leukocyte oxidase: defective activity in chronic granulomatous disease.白细胞氧化酶：慢性肉芽肿病中的活性缺陷
Science. 1967 Feb 17;155(3764):835-6. doi: 10.1126/science.155.3764.835.
7
Relationship of glycolytic and oxidative metabolism to particle entry and destruction in phagocytosing cells.糖酵解和氧化代谢与吞噬细胞中颗粒摄入及破坏的关系。
Nature. 1966 Sep 17;211(5055):1272-6. doi: 10.1038/2111272a0.
8
Acute bacterial infection in kwashiorkor and marasmus.夸希奥科病和消瘦症中的急性细菌感染。
Br Med J. 1968 Feb 17;1(5589):407-9. doi: 10.1136/bmj.1.5589.407.
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