Cope F W
Physiol Chem Phys. 1979;11(1):93-4.
High potassium together with low sodium in diet and intravenous fluids has been observed clinically by Sodi-Pallares to have a beneficial effect on chronic heart failure and on acute myocardial infarction. Recent studies from the laboratory of Ling indicate that high potassium, low sodium environments can partially restore damaged cell proteins to their normal undamaged configuration. It follows that by this mechanism cell proteins damaged by the chronic or acute hypoxia of heart disease are probably partly repaired when high potassium, low sodium therapy is used.
临床上,索迪 - 帕拉雷斯观察到,饮食和静脉输液中高钾低钠对慢性心力衰竭和急性心肌梗死有有益作用。凌实验室最近的研究表明,高钾低钠环境可使受损的细胞蛋白部分恢复到正常的未受损构型。由此可见,通过这种机制,当采用高钾低钠疗法时,因心脏病慢性或急性缺氧而受损的细胞蛋白可能会得到部分修复。