Huse-Kleinstoll G, Jungmann H, Schlenker M
Z Kardiol. 1979 Aug;68(8):570-4.
In 51 healthy young people the carotid arterial pulse wave was registered externally during bicycle-exercise in a lying position. The ejection time in relation to the duration of diastole (not pulse period or heart rate!) increased significantly. These results are compared with measurements made by Schulz (15) who found normal ejection times in tachycardia provoked by pacer-stimulation and shortened values during isoproterenol-induced tachycardia. Women have longer ejection times than men especially under physical stress. In 18 patients suffering from aortic insufficiency, ejection times were slightly prolonged and in 28 patients who had a systolic pressure gradient of more than 20 mm Hg between the left ventricle and the aorta ejection times were markedly prolonged. There is also a significant positive correlation between ejection time and pressure gradient. The authors consider that the autonomic innervation plays an important role in the duration of ejection time in normal subjects while in patients with aortic heart disease the ejection time is predominantly influenced by mechanical factors. For the diagnosis of the severity of aortic stenosis measurements of ejection time are only useful in connection with other clinical parameters (pulse pressure, creast time of the arterial pulse wave).
在51名健康年轻人中,于卧位进行自行车运动时对外侧颈动脉脉搏波进行记录。与舒张期时长相关的射血时间(而非脉搏周期或心率!)显著增加。将这些结果与舒尔茨(15)的测量结果进行比较,舒尔茨发现在起搏器刺激诱发的心动过速中射血时间正常,而在异丙肾上腺素诱发的心动过速中射血时间缩短。女性的射血时间比男性长,尤其是在身体应激状态下。在18例主动脉瓣关闭不全患者中,射血时间略有延长;在28例左心室与主动脉之间收缩压梯度超过20 mmHg的患者中,射血时间明显延长。射血时间与压力梯度之间也存在显著正相关。作者认为,自主神经支配在正常受试者射血时间的持续中起重要作用,而在主动脉性心脏病患者中,射血时间主要受机械因素影响。对于主动脉瓣狭窄严重程度的诊断,射血时间的测量仅与其他临床参数(脉压、动脉脉搏波的波峰时间)结合使用才有用。