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Conformational changes, inactivation, and dissociation of pigeon liver fatty acid synthetase complex. Effects of ionic strength, pH, and temperature.

作者信息

Kumar S, Muesing R A, Porter J W

出版信息

J Biol Chem. 1972 Aug 10;247(15):4749-62.

PMID:5065950
Abstract
摘要

相似文献

1
Conformational changes, inactivation, and dissociation of pigeon liver fatty acid synthetase complex. Effects of ionic strength, pH, and temperature.鸽肝脂肪酸合成酶复合体的构象变化、失活及解离。离子强度、pH值和温度的影响。
J Biol Chem. 1972 Aug 10;247(15):4749-62.
2
Fatty acid synthetase of chicken liver. Reversible dissociation into two nonidentical subcomplexes of similar size.鸡肝脂肪酸合成酶。可逆解离为两个大小相似但不同的亚复合物。
J Biol Chem. 1972 May 10;247(9):2689-98.
3
The effects of reduced nicotinamide adenine dinucleotide phosphate, its structural analogues, and coenzyme A and its derivatives on the rate of dissociation, conformation, and enzyme activity of the pigeon liver fatty acid synthetase complex.还原型烟酰胺腺嘌呤二核苷酸磷酸及其结构类似物、辅酶A及其衍生物对鸽肝脂肪酸合成酶复合体的解离速率、构象和酶活性的影响。
J Biol Chem. 1971 Dec 25;246(24):7780-9.
4
Mechanism of dissociation of pigeon liver fatty acid synthetase complex into half-molecular weight subunits and their reassociation to enzymatically active complex.鸽肝脂肪酸合成酶复合体解离为半分子量亚基及其重新缔合成具有酶活性复合体的机制。
Biochem Biophys Res Commun. 1970 Aug 24;40(4):825-32. doi: 10.1016/0006-291x(70)90977-0.
5
[Rabbit liver palmitate synthetase. Purification; physicochemical properties of the native enzyme; study of subunits; study of the secondary and tertiary structure as a function of ionic strength (author's transl)].[兔肝棕榈酸合成酶。纯化；天然酶的物理化学性质；亚基研究；作为离子强度函数的二级和三级结构研究（作者译）]
Biochim Biophys Acta. 1974 Apr 26;348(1):94-114.
6
Factors affecting the reassociation and reactivation of the half-molecular weight nonidentical subunits of pigeon liver fatty acid synthetase.影响鸽肝脂肪酸合成酶半分子量不同亚基重新缔合及重新激活的因素。
J Biol Chem. 1975 Mar 10;250(5):1814-23.
7
The isolation of acyl carrier protein from the pigeon liver fatty acid synthetase complex1 II.从鸽肝脂肪酸合成酶复合体1 II中分离酰基载体蛋白。
Biochem Biophys Res Commun. 1974 Sep 9;60(1):158-65. doi: 10.1016/0006-291x(74)90186-7.
8
Studies on the reactivity of the essential sulfhydryl groups as a conformational probe for the fatty acid synthetase of chicken liver. Inactivation by 5,5'-dithiobis-(2-nitrobenzoic acid) and intersubunit cross-linking of the inactivated enzyme.关于必需巯基作为鸡肝脂肪酸合成酶构象探针的反应性研究。5,5'-二硫代双（2-硝基苯甲酸）对其的失活作用以及失活酶的亚基间交联。
J Biol Chem. 1985 Sep 15;260(20):11375-87.
9
Substrate inhibition of pigeon liver fatty acid synthetase and optimum assay conditions for over-all synthetase activity.鸽肝脂肪酸合成酶的底物抑制作用及整体合成酶活性的最佳测定条件。
Arch Biochem Biophys. 1974 Jul;163(1):324-31. doi: 10.1016/0003-9861(74)90483-4.
10
Role of cysteine and 4'-phosphopantetheine in the inactivation of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A.半胱氨酸和4'-磷酸泛酰巯基乙胺在S-(4-溴-2,3-二氧代丁基)-辅酶A使鸽肝脂肪酸合成酶失活中的作用
Biochem Biophys Res Commun. 1982 Jan 29;104(2):517-22. doi: 10.1016/0006-291x(82)90667-2.

引用本文的文献

1
Fatty acid synthetase of bovine mammary: Properties and products.牛乳腺脂肪酸合成酶：特性与产物
Lipids. 1975 Apr;10(4):227-37. doi: 10.1007/BF02532485.
2
Transformations of a large aggregate of hydroxycinnamate hydroxylase to lower molecular weight forms by sulfhydryl agents in green leaves of sorghum.在高粱绿叶中，巯基试剂将大量羟基肉桂酸羟化酶聚集体转化为较低分子量形式。
Plant Physiol. 1975 Feb;55(2):145-9. doi: 10.1104/pp.55.2.145.
3
Quaternary structure of human fatty acid synthase by electron cryomicroscopy.通过电子冷冻显微镜观察人脂肪酸合酶的四级结构
Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):138-43. doi: 10.1073/pnas.012589499. Epub 2001 Dec 26.
4
Characterization of fatty acid synthase monomers restrained from reassociating by immobilization to a solid support.通过固定在固体支持物上而抑制重新缔合的脂肪酸合酶单体的表征。
Biochem J. 1993 Jun 1;292 ( Pt 2)(Pt 2):361-4. doi: 10.1042/bj2920361.
5
Presence of two polypeptide chains comprising fatty acid synthetase.存在由脂肪酸合成酶组成的两条多肽链。
Proc Natl Acad Sci U S A. 1975 May;72(5):1940-4. doi: 10.1073/pnas.72.5.1940.