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[由细菌L型引起的实验性肺炎的治疗与预防]

[Treatment and prevention of experimental pneumonias, caused by L forms of bacteria].

作者信息

Ermakova G L, Martynova V A, Vlasova A G, Golosova T V, Nemenova N M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1975 Jun(6):115-22.

PMID:50680
Abstract

On a model of experimental pneumonia in mice caused by the L-forms of bacteria against the background of diminished immunity a study was made of the therapeutic efficacy of penicillin, lincomycin, lysozyme and gamma-globulin. Lincomycin, particularly in combination with biologically-active preparations, proved to be expedience for the treatment and prophylaxis of pneumonia caused by the mentioned bacteria; a rapid arrest of pneumonic process occurred and more animals survived. In the greater percentage of cases the use of penicillin was accompanied by generalization of the process.

摘要

在免疫力降低背景下由细菌L型引起的小鼠实验性肺炎模型上,研究了青霉素、林可霉素、溶菌酶和γ球蛋白的治疗效果。结果表明,林可霉素,特别是与生物活性制剂联合使用时,对治疗和预防上述细菌引起的肺炎是适宜的;肺炎进程迅速得到控制,更多动物存活下来。在较大比例的病例中,使用青霉素会伴随病情的扩散。

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1
[Treatment and prevention of experimental pneumonias, caused by L forms of bacteria].[由细菌L型引起的实验性肺炎的治疗与预防]
Zh Mikrobiol Epidemiol Immunobiol. 1975 Jun(6):115-22.
2
[Experimental infection of mice with bacterial L forms against a background of immunodepressants].[在免疫抑制剂背景下小鼠的细菌L型实验性感染]
Zh Mikrobiol Epidemiol Immunobiol. 1974 Apr;51(4):91-4.
3
A comparison of lincomycin and penicillin in the treatment of group A streptococcal infections: speculation on the "L" form as a mechanism of recurrence.
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The use of 7-chlorolincomycin in the treatment of childhood respiratory disease.7-氯林可霉素在儿童呼吸道疾病治疗中的应用。
Med J Aust. 1973 Mar 3;1(9):439-41. doi: 10.5694/j.1326-5377.1973.tb110477.x.
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Lincomycin therapy of pneumonia: clinical experience with 50 patients.林可霉素治疗肺炎:50例患者的临床经验。
South Med J. 1967 Feb;60(2):203-8. doi: 10.1097/00007611-196702000-00025.
6
Pneumonia.肺炎
Am Fam Physician. 1972 Dec;6(6):84-91.
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Antibiotics in the treatment of burns.抗生素在烧伤治疗中的应用
Surg Clin North Am. 1970 Dec;50(6):1311-23. doi: 10.1016/s0039-6109(16)39290-8.
8
Lincomycin in hospital practice.医院实践中的林可霉素。
Can Med Assoc J. 1965 Sep 25;93(13):685-91.
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[Research with a gamma globulin preparation. 3. Tests on white mice to prove a synergistic protective effect of the combination of colostral bovine gamma globulin with penicillin-streptomycin].
Berl Munch Tierarztl Wochenschr. 1968 Dec 15;81(24):483-5.
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[Treatment of diarrhea in association with dystrophic penicillin-streptomycin-gamma globulin].[营养不良性青霉素 - 链霉素 - 丙种球蛋白联合腹泻的治疗]
Acta Pediatr Esp. 1956 Apr;14(160):309-16.