The pharmacokinetics of an oral form of carbenicillin in patients with renal failure.
作者信息
Bailey R R, Eastwood J B, Vaughan R B
出版信息
Postgrad Med J. 1972 Jul;48(561):422-6. doi: 10.1136/pgmj.48.561.422.
Abstract
An orally active ester of carbenicillin was administered to patients with varying degrees of renal dysfunction. The peak serum levels and serum half-life were found to be increased in patients with renal failure. Urine levels, however, in these patients were above the minimum inhibitory concentration for the majority of urinary tract pathogens.
摘要
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本文引用的文献
1
Evaluation of an indanyl ester of carbenicillin.
Antimicrob Agents Chemother (Bethesda). 1970;10:223-6.
2
Human pharmacology and clinical evaluation of an oral carbenicillin preparation.
Clin Pharmacol Ther. 1971 May-Jun;12(3):525-30. doi: 10.1002/cpt1971123525.
3
Carbenicillin: a new semisynthetic penicillin active against Pseudomonas pyocyanea.
Br Med J. 1967 Jul 8;3(5557):75-8. doi: 10.1136/bmj.3.5557.75.
4
Carbenicillin administration in patients with severe renal failure.
Br Med J. 1968 Feb 24;1(5590):486-7. doi: 10.1136/bmj.1.5590.486.
5
Oral administration of a new carbenicillin in the treatment of urinary tract infection.
Br J Urol. 1972 Apr;44(2):235-9. doi: 10.1111/j.1464-410x.1972.tb10070.x.
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