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长期给予不同烈性酒和红酒对大鼠肝脏的影响。一项组织学和生物化学研究。

Effect of long-term administration of different hard liquors and red wine on the rat liver. A histological and biochemical study.

作者信息

Jordö L, Olsson R

出版信息

Acta Pathol Microbiol Scand A. 1975 Jul;83(4):345-54. doi: 10.1111/j.1699-0463.1975.tb01882.x.

Abstract

Male rats were given 50 per cent of calories as ethanol, whisky, brandy, gin and red wine for 8-9 months together with moderate or low protein and vitamin supply. Histological studies at sacrifice failed to detect signs of hepatotoxicity, but biochemical studies indicated that at least red wine and whisky produced more undesirable effects on the liver than ethanol.

摘要

给雄性大鼠喂食含50%热量的乙醇、威士忌、白兰地、杜松子酒和红酒,持续8 - 9个月,同时给予适量或低量的蛋白质和维生素。处死时的组织学研究未发现肝毒性迹象,但生化研究表明,至少红酒和威士忌对肝脏产生的不良影响比乙醇更多。

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Long term toxicity study with alcohol and 4-methylpyrazole in rat.酒精与4-甲基吡唑对大鼠的长期毒性研究。
Acta Pathol Microbiol Scand A. 1974 Jul;82(4):534-8. doi: 10.1111/j.1699-0463.1974.tb00383.x.

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