同一家族三代人中的葡萄膜恶性黑色素瘤。

Uveal malignant melanoma in three generations of the same family.

作者信息

Walker J P, Weiter J J, Albert D M, Osborn E L, Weichselbaum R R

出版信息

Am J Ophthalmol. 1979 Oct;88(4):723-6. doi: 10.1016/0002-9394(79)90672-x.

Abstract

Three patients in three successive generations from the same family had choroidal malignant melanoma. The third generation patient had multiple primary malignancies; his siblings also had multiple malignancies. Chromosome studies of the third generation patient revealed no abnormality. To the best of our knowledge, this is the second such pedigree reported.

摘要

同一家族连续三代中有三名患者患有脉络膜恶性黑色素瘤。第三代患者患有多种原发性恶性肿瘤；他的兄弟姐妹也患有多种恶性肿瘤。对第三代患者进行的染色体研究未发现异常。据我们所知，这是报道的第二个此类家系。