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An explanation of the antiandrogenic properties of 6 -bromo-17 -hydroxy-17 -methyl-4-oxa-5 -androstane-3-one.

作者信息

Mangan F R, Mainwaring W I

出版信息

Steroids. 1972 Sep;20(3):331-43. doi: 10.1016/0039-128x(72)90092-x.

DOI:10.1016/0039-128x(72)90092-x
PMID:5073580
Abstract
摘要

相似文献

1
An explanation of the antiandrogenic properties of 6 -bromo-17 -hydroxy-17 -methyl-4-oxa-5 -androstane-3-one.6-溴-17-羟基-17-甲基-4-氧杂-5-雄甾烷-3-酮的抗雄激素特性解释
Steroids. 1972 Sep;20(3):331-43. doi: 10.1016/0039-128x(72)90092-x.
2
The biochemical basis for the antagonism by BOMT of the effects of dihydrotesterone on the rat ventral prostate gland.BOMT对二氢睾酮作用于大鼠前列腺腹侧叶产生拮抗作用的生化基础。
Gynecol Invest. 1971;2(1):300-4. doi: 10.1159/000301871.
3
Biologic and biochemical effects of anti-androgens on rat ventral prostate.抗雄激素对大鼠前列腺腹叶的生物学和生化效应。
Acta Endocrinol (Copenh). 1974 Feb;75(2):385-97. doi: 10.1530/acta.0.0750385.
4
Synandrogenic and antiandrogenic effect of progestins: comparison with nonprogestational antiandrogens.孕激素的协同雄激素作用和抗雄激素作用：与非孕激素类抗雄激素药物的比较。
Endocrinology. 1974 Dec;95(6):1589-99. doi: 10.1210/endo-95-6-1589.
5
Androgen receptor binding and antiandrogenic activity of some 4,5-secoandrostanes and ring B cyclopropanoandrostanes.某些4,5-开环雄甾烷和B环环丙基雄甾烷的雄激素受体结合及抗雄激素活性
J Steroid Biochem. 1982 Sep;17(3):331-4.
6
Screening for antiandrogenic activity of some 4,5-cyclo-A-homo-B-nor-and-androstane derivatives.某些4,5-环-A-高-B-降-雄甾烷衍生物的抗雄激素活性筛选
J Steroid Biochem. 1977 Sep;8(9):939-41. doi: 10.1016/0022-4731(77)90190-x.
7
Rat fetal target organ delta-5, 3 beta-hydroxysteroid dehydrogenase: effect of cyanoketone and cyproterone acetate.
Endocrinology. 1973 Apr;92(4):1043-50. doi: 10.1210/endo-92-4-1043.
8
A new antiandrogen, 6alpha-bromo-17 beta-hydroxy-17 alpha-methyl-4-oxa-5 alpha-androstan-3-one.一种新型抗雄激素药物，6α-溴-17β-羟基-17α-甲基-4-氧杂-5α-雄甾烷-3-酮。
Experientia. 1970 Jan 15;26(1):9-10. doi: 10.1007/BF01900355.
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The effect of androgenic hormones on the reduced nicotinamide adenine dinucleotide phosphate:delta-4-3-ketosteroid 5 alpha-oxidoreductase of rat ventral prostate.
Endocrinology. 1973 Sep;93(3):581-92. doi: 10.1210/endo-93-3-581.
10
Mode of spironolactone anti-androgenic action: inhibition of androstanolone binding to rat prostate androgen receptor.螺内酯抗雄激素作用模式：抑制雄烷醇与大鼠前列腺雄激素受体的结合。
Mol Cell Endocrinol. 1974 Dec;2(1):59-67. doi: 10.1016/0303-7207(74)90012-4.

引用本文的文献

1
Effect of steroids with antiandrogenic properties on androgenic and myotrophic activity of testosterone and some of its derivatives.具有抗雄激素特性的类固醇对睾酮及其某些衍生物的雄激素活性和促肌营养活性的影响。
Neurosci Behav Physiol. 1980 May-Jun;10(3):227-31. doi: 10.1007/BF01182216.
2
Studies on the role of the sex-hormone-binding globulin (SHBG) in prostatic gland hypertrophy in men. II. In vitro research.关于性激素结合球蛋白（SHBG）在男性前列腺肥大中作用的研究。II. 体外研究。
Int Urol Nephrol. 1984;16(3):211-7. doi: 10.1007/BF02082565.
3
The control of the form and function of the ribosomes in androgen-dependent tissues by testosterone.
睾酮对雄激素依赖组织中核糖体的形态和功能的控制。
Biochem J. 1973 Jul;134(3):795-805. doi: 10.1042/bj1340795.
4
Studies on the form and synthesis of messenger ribonucleic acid in the rat ventral prostate gland, including its tissue-specific stimulation by androgens.大鼠腹侧前列腺中信使核糖核酸的形式与合成研究，包括雄激素对其组织特异性的刺激作用。
Biochem J. 1974 Mar;137(3):513-24. doi: 10.1042/bj1370513.
5
A reappraisal of the effects of adenosine 3':5'-cyclic monophosphate on the function and morphology of the rat prostate gland.对3':5'-环磷酸腺苷对大鼠前列腺功能和形态影响的重新评估。
Biochem J. 1973 May;134(1):129-42. doi: 10.1042/bj1340129.
6
The use of deoxyribonucleic acid-cellulose chromatography and isoelectric focusing for the characterization and partial purification of steroid-receptor complexes.利用脱氧核糖核酸-纤维素色谱法和等电聚焦法对类固醇受体复合物进行表征和部分纯化。
Biochem J. 1973 May;134(1):113-27. doi: 10.1042/bj1340113.
7
Studies on the local activity of antiandrogens at the molecular and histological level.
Mol Biol Rep. 1986;11(2):99-105. doi: 10.1007/BF00364821.
8
The androgenic regulation of the activities of enzymes engaged in the synthesis of deoxyribonucleic acid in rat ventral prostate gland.大鼠前列腺腹侧腺中参与脱氧核糖核酸合成的酶活性的雄激素调节。
Biochem J. 1975 Oct;152(1):1-16. doi: 10.1042/bj1520001.
9
Androgen-dependent synthesis of basic secretory proteins by the rat seminal vesicle.大鼠精囊雄激素依赖性碱性分泌蛋白的合成。
Biochem J. 1976 Aug 15;158(2):271-82. doi: 10.1042/bj1580271.
10
Nuclear components responsible for the retention of steroid--receptor complexes, especially from the standpoint of the specifcity of hormonal responses.负责甾体受体复合物保留的核成分，特别是从激素反应特异性的角度来看。
Biochem J. 1976 Apr 15;156(1):129-41. doi: 10.1042/bj1560129.