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1
Total number of individuals affected by a single deleterious mutation in a finite population.有限群体中受单个有害突变影响的个体总数。
Am J Hum Genet. 1972 Nov;24(6 Pt 1):667-79.
2
Total number of individuals affected by deleterious mutant genes in a finite population.有限群体中受有害突变基因影响的个体总数。
Ann Hum Genet. 1975 Jan;38(3):333-40. doi: 10.1111/j.1469-1809.1975.tb00618.x.
3
Prevalence of glucose-6-phosphate dehydrogenase deficiency in sickle-cell disease.镰状细胞病中葡萄糖-6-磷酸脱氢酶缺乏症的患病率。
N Engl J Med. 1974 Apr 11;290(15):826-8. doi: 10.1056/NEJM197404112901504.
4
Distribution of gene frequencies in a geographically structured population. II. Distribution of deleterious genes and of lethal genes.基因频率在地理结构种群中的分布。II. 有害基因和致死基因的分布。
Ann Hum Genet. 1972 Apr;35(4):425-32. doi: 10.1111/j.1469-1809.1957.tb01867.x.
5
Migrant populations and the diffusion of the sickle-cell gene.
Ann Intern Med. 1973 Aug;79(2):258-64. doi: 10.7326/0003-4819-79-2-258.
6
Total number of individuals affected by a single sex-linked deleterious mutation in a finite population.有限群体中受单个X连锁有害突变影响的个体总数。
Am J Hum Genet. 1973 Nov;25(6):598-603.
7
Mass screening programs for sickle cell hemoglobin.镰状细胞血红蛋白大规模筛查项目。
JAMA. 1972 Jul 31;221(5):500-2. doi: 10.1001/jama.1972.03200180042012.
8
Further characterization of the long-run population distribution of a deleterious gene.
Theor Popul Biol. 1980 Aug;18(1):31-43. doi: 10.1016/0040-5809(80)90038-6.
9
The red cell acid phosphatase polymorphism in Southern Africa: population data and studies on the R, RA and RB phenotypes.南部非洲的红细胞酸性磷酸酶多态性：群体数据及R、RA和RB表型研究
Ann Hum Genet. 1972 Apr;35(4):379-91.
10
Frequency of sickling disorders in U.S. blacks.美国黑人镰状细胞病的发病率。
N Engl J Med. 1973 Jan 4;288(1):31-3. doi: 10.1056/NEJM197301042880108.

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1
Estimating the selective effects of heterozygous protein-truncating variants from human exome data.从人类外显子数据估计杂合蛋白截短变异的选择效应。
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2
An estimate of the average number of recessive lethal mutations carried by humans.对人类携带的隐性致死突变平均数量的估计。
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3
Shortcut predictions for fitness properties at the mutation-selection-drift balance and for its buildup after size reduction under different management strategies.在突变 - 选择 - 漂变平衡下以及在不同管理策略下种群数量减少后适应性特征积累过程中的适应性属性捷径预测。
Genetics. 2007 Jun;176(2):983-97. doi: 10.1534/genetics.106.065730. Epub 2007 Apr 15.
4
Analysis of the estimators of the average coefficient of dominance of deleterious mutations.有害突变显性平均系数估计值的分析。
Genetics. 2004 Oct;168(2):1053-69. doi: 10.1534/genetics.104.027706.
5
Evolution of functionally conserved enhancers can be accelerated in large populations: a population-genetic model.功能保守增强子的进化在大种群中可能会加速：一个种群遗传学模型。
Proc Biol Sci. 2002 May 7;269(1494):953-60. doi: 10.1098/rspb.2002.1968.
6
Clusters of identical new mutation in the evolutionary landscape.进化图景中相同新突变的簇集。
Genetica. 1996 Oct;98(2):149-60. doi: 10.1007/BF00121363.
7
Comparing mutational variabilities.比较突变变异性。
Genetics. 1996 Jul;143(3):1467-83. doi: 10.1093/genetics/143.3.1467.
8
A potential hazard: explosive production of mutations by induction of mutators.一种潜在危害：通过诱导突变体产生突变的爆发性情况。
Environ Health Perspect. 1973 Dec;6:207-10. doi: 10.1289/ehp.7306207.
9
Total number of individuals affected by a single sex-linked deleterious mutation in a finite population.有限群体中受单个X连锁有害突变影响的个体总数。
Am J Hum Genet. 1973 Nov;25(6):598-603.
10
The age of a rare mutant gene in a large population.一个大群体中罕见突变基因的年代。
Am J Hum Genet. 1974 Nov;26(6):669-73.

本文引用的文献

1
The Average Number of Generations until Fixation of a Mutant Gene in a Finite Population.有限种群中突变基因固定之前的平均世代数。
Genetics. 1969 Mar;61(3):763-71. doi: 10.1093/genetics/61.3.763.
2
The average number of generations until extinction of an individual mutant gene in a finite population.有限种群中单个突变基因灭绝前的平均世代数。
Genetics. 1969 Nov;63(3):701-9. doi: 10.1093/genetics/63.3.701.
3
The frequency distribution of lethal chromosomes in finite populations.有限群体中致死染色体的频率分布。
Proc Natl Acad Sci U S A. 1968 Jun;60(2):517-24. doi: 10.1073/pnas.60.2.517.
4
Total number of individuals affected by a single deleterious mutation in large populations.
Theor Popul Biol. 1971 Dec;2(4):426-30. doi: 10.1016/0040-5809(71)90031-1.
5
Extinction time of deleterious mutant genes in large populations.大群体中有害突变基因的灭绝时间。
Theor Popul Biol. 1971 Dec;2(4):419-25. doi: 10.1016/0040-5809(71)90030-x.
6
Public health and long-term genetic implications of intrauterine diagnosis and selective abortion.
Birth Defects Orig Artic Ser. 1971 Apr;7(5):22-32.

Total number of individuals affected by a single deleterious mutation in a finite population.

作者信息

Li W H, Nei M

出版信息

Am J Hum Genet. 1972 Nov;24(6 Pt 1):667-79.

PMID:5082917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1762297/
Abstract
摘要