[大鼠肝细胞核与细胞质中核酸外切酶对多聚腺苷酸的降解活性]
[Enzymatic exonuclease poly(A) degradation activity in liver nucleus and cytoplasm of rats].
作者信息
Rossini G P, Drusiani F, Corti A
出版信息
Boll Soc Ital Biol Sper. 1979 May 30;55(10):936-8.
PMID:508406
Abstract
Poly(A) degrading activities are detectable in nuclear, nucleoplasmic, cytoplasmic extracts and chromatin preparations from rat liver. More than 75% of the activity has been found within the nucleus; most of the nuclear activity is chromatin bound. Poly(A) degradation appears to occur largely via exonucleolitic cleavage.
摘要
在大鼠肝脏的细胞核、核质、细胞质提取物以及染色质制剂中可检测到聚腺苷酸（Poly(A)）降解活性。已发现超过75%的活性存在于细胞核内；大部分核活性与染色质结合。聚腺苷酸（Poly(A)）降解似乎主要通过核酸外切酶裂解发生。
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