庆大霉素在人房水中的渗透与衰减
Gentamicin penetration and decay in the human aqueous.
作者信息
Hillman J S, Jacobs S I, Garnett A J, Kheskani M B
出版信息
Br J Ophthalmol. 1979 Nov;63(11):794-6. doi: 10.1136/bjo.63.11.794.
Abstract
The penetration of gentamicin into human aqueous was measured after intensive drops or subconjunctival injection of the antibiotic. The drop regimen proved ineffective in producing a therapeutically effective level. After a single 40 mg subconjunctival injection an effective concentration was achieved in 2 hours and maintained for 24 hours. The significance of these findings is discussed with respect to therapeutic implications.
摘要
在频繁滴眼或结膜下注射庆大霉素后，测定了庆大霉素在人房水中的渗透情况。滴眼方案被证明无法产生治疗有效的水平。单次结膜下注射40毫克后，在2小时内达到有效浓度，并维持24小时。就治疗意义对这些发现的重要性进行了讨论。
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本文引用的文献
1
Subconjunctival gentamicin.结膜下注射庆大霉素。
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Penicillin combined with gentamicin or streptomycin: synergism against enterococci.青霉素与庆大霉素或链霉素联合使用：对肠球菌有协同作用。
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