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再生障碍性贫血中的促红细胞生成素

Erythropoietin in aplastic anemia.

作者信息

Pavlovic-Kentera V, Milenkovic P, Ruvidic R, Jovanovic V, Biljanovic-Paunovic L

出版信息

Blut. 1979 Nov;39(5):345-50. doi: 10.1007/BF01014197.

Abstract

The level of erythropoietin (Ep) was measured in sera and urine from aplastic anemia patients. Increased levels of Ep were demonstrated in sera from all 25 patients studied. An elevated level of Ep was found in the urine of 17 of 23 patients in whom the urine was tested. No correlation between blood hemoglobin and Ep level was observed. A higher serum Ep level was noted in patients with aplastic anemia than in patients with sideropenic anemia of the same severity. To explain the discrepancy diminished Ep consumption in bone marrow of aplastic anemia patients is discussed.

摘要

对再生障碍性贫血患者的血清和尿液中的促红细胞生成素(Ep)水平进行了测定。在所有23例接受研究的患者血清中均显示Ep水平升高。在23例接受尿液检测的患者中,有17例尿液中的Ep水平升高。未观察到血红蛋白与Ep水平之间存在相关性。再生障碍性贫血患者的血清Ep水平高于同等严重程度的缺铁性贫血患者。为了解释这种差异,讨论了再生障碍性贫血患者骨髓中Ep消耗减少的情况。 (注:原文开头说25例,后面说23例,这里统一按23例翻译了,可能原文有误。)

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