采用液相色谱-电化学检测法测定4-羟基-3-甲氧基苯乙酸（高香草酸）
Assay of 4-hydroxy-3-methoxyphenylacetic (homovanillic) acid by liquid chromatography with electrochemical detection.
作者信息
Morrisey J L, Shihabi Z K
出版信息
Clin Chem. 1979 Dec;25(12):2045-7.
PMID:509705
Abstract
We describe a method for the assay of urinary 4-hydroxy-3-methoxyphenylacetic acid (homovanillic acid), based on its separation on a microparticulate reversed-phase column and direct electrochemical detection. Patients with neuroblastoma, pheochromocytoma, and Parkinson's disease have increased amounts of this compound in their urine.
摘要
我们描述了一种检测尿中4-羟基-3-甲氧基苯乙酸（高香草酸）的方法，该方法基于其在微粒反相柱上的分离及直接电化学检测。患有神经母细胞瘤、嗜铬细胞瘤和帕金森病的患者尿中该化合物含量会增加。
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