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通过核磁共振检测冻干髓鞘中的分子运动。

Detection of molecular motion in lyophilized myelin by nuclear magnetic resonance.

作者信息

Lecar H, Ehrenstein G, Stillman I

出版信息

Biophys J. 1971 Feb;11(2):140-5. doi: 10.1016/S0006-3495(71)86203-3.

Abstract

Proton resonance spectroscopy was used to determine the state of the hydrocarbon regions in lyophilized and resuspended samples of nerve myelin. Measurements of the resonance line width indicate considerable freedom of motion within the hydrocarbon moiety of the myelin samples. Sharp thermal transitions of the line width were observed, suggesting that lyophilized myelin is in a liquid crystalline state.

摘要

质子共振光谱法被用于测定神经髓鞘冻干和重悬样品中烃区域的状态。共振线宽的测量表明髓鞘样品的烃部分内存在相当大的运动自由度。观察到线宽有明显的热转变,这表明冻干的髓鞘处于液晶状态。

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引用本文的文献

本文引用的文献

1
STABILITY OF THE MYELIN MEMBRANE.髓磷脂膜的稳定性
Science. 1965 Mar 5;147(3662):1099-107. doi: 10.1126/science.147.3662.1099.
4
Myelin: dynamic or stable?髓磷脂:动态还是稳定?
J Gen Physiol. 1968 May;51(5):Suppl:8S+.
5
Nuclear magnetic resonance studies of erythrocyte membranes.红细胞膜的核磁共振研究。
J Mol Biol. 1968 Jan 14;31(1):101-14. doi: 10.1016/0022-2836(68)90058-2.
6
Structural parameters of nerve myelin.神经髓鞘的结构参数
Proc Natl Acad Sci U S A. 1969 Jul;63(3):604-11. doi: 10.1073/pnas.63.3.604.

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