Pandya S S, Chulawala R G
Int J Lepr Other Mycobact Dis. 1975 Jan-Mar;43(1):32-5.
The pattern of extrafusal and intrafusal innervation was studied in muscle biopsies from the flexor carpi ulnaris and biceps brachii muscles, which were clinically unimpaired. Smudginess and enlargement of the motor end plates were the most definitely abnormal feature of the extrafusal innervation pattern; the intrafusal fibers, on the other hand, were either unremarkable or showed increased tortuosity, beading and in more extreme cases of grossly complicated intertwining pattern. Bacilli were frequently found in the spindles, no component being spared. The study emphasizes the significant involvement of striated muscle in leprosy, a fact not revealed by clinical examination alone.
对临床未受损的尺侧腕屈肌和肱二头肌的肌肉活检样本进行了研究，观察了肌外肌和肌梭内的神经支配模式。运动终板的模糊和增大是肌外神经支配模式最明显的异常特征；另一方面，肌梭内纤维要么无明显异常，要么表现出曲折度增加、串珠样改变，在更极端的情况下，呈现出极为复杂的交织模式。在肌梭中经常发现杆菌，无一部位幸免。该研究强调了麻风病中横纹肌的显著受累情况，这一事实仅凭临床检查无法揭示。
