无菌性脑膜炎，蒙特利尔，1969年：一项临床与实验室研究。
Aseptic meningitis, Montreal, 1969: a clinical and laboratory study.
作者信息
Groh V, Masson A M, Spence L, Brodie H R
出版信息
Can Med Assoc J. 1971 Feb 20;104(4):296-8.
During the summer and fall of 1969 an outbreak of aseptic meningitis occurred in Montreal and its environs. Forty-four patients were admitted to the infectious disease ward of The Montreal Children's Hospital in August, September and October. Half of the patients were in the age group 6 to 10 years. The ratio of males to females was two to one. Patients showed the typical signs and symptoms of aseptic meningitis, namely fever, vomiting, headache, neck stiffness and pleocytosis of the cerebrospinal fluid.Viruses were recovered from 19 (43%) of the 44 cases. The predominant virus in the outbreak was a non-hemagglutinating strain of echovirus 6. Other virus types isolated in the outbreak were echovirus 7, coxsackievirus A9 and coxsackievirus B4. Serological investigations confirmed the validity of the echovirus isolations and identified additional cases.
1969年夏秋之际，蒙特利尔及其周边地区爆发了无菌性脑膜炎疫情。8月、9月和10月期间，有44名患者被收治于蒙特利尔儿童医院的传染病病房。其中一半患者年龄在6至10岁之间。男女比例为2比1。患者表现出无菌性脑膜炎的典型症状和体征，即发热、呕吐、头痛、颈部僵硬以及脑脊液中细胞增多。在44例病例中，有19例（43%）检测出病毒。此次疫情中的主要病毒是埃可病毒6型的一种非血凝毒株。此次疫情中分离出的其他病毒类型有埃可病毒7型、柯萨奇病毒A9型和柯萨奇病毒B4型。血清学调查证实了埃可病毒分离结果的有效性，并确定了更多病例。
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