Simon C, Bastiani P
Endocr Res Commun. 1979;6(2):149-58. doi: 10.1080/07435807909061102.
The isotopic equilibrium method was used for a 60-day period to follow iodine turnover in control and hypophysectomized rats. After the suppression of TSH by hypophysectomy, only the captured iodide is used for iodination of thyroglobulin, the iodide recycling being abolished. In unstimulated gland, two metabolically distinct iodide compartments do exist which differ either in their chemical form or in their morphological distribution, or both.
采用同位素平衡法,对正常大鼠和垂体切除大鼠进行为期60天的碘周转追踪。垂体切除术后促甲状腺激素(TSH)被抑制,仅捕获的碘化物用于甲状腺球蛋白的碘化,碘化物循环被消除。在未受刺激的腺体中,确实存在两个代谢上不同的碘化物区室,它们在化学形式或形态分布上有所不同,或两者皆有差异。