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通过吸入乙醇在小鼠中产生酒精依赖：对戒断反应进行分级

Alcohol dependence produced in mice by inhalation of ethanol: grading the withdrawal reaction.

作者信息

Goldstein D B, Pal N

出版信息

Science. 1971 Apr 16;172(3980):288-90. doi: 10.1126/science.172.3980.288.

DOI:10.1126/science.172.3980.288
PMID:5102255
Abstract

Intoxicating blood levels of ethanol are maintained for several days in mice housed in an atmosphere of ethanol vapor. On removal from the alcohol, all the mice develop withdrawal signs. The signs can be graded to indicate the time course and intensity of the withdrawal reaction.

摘要

将小鼠置于乙醇蒸汽环境中，其血液中的乙醇中毒水平会维持数天。一旦移除酒精，所有小鼠都会出现戒断症状。这些症状可以分级，以表明戒断反应的时间进程和强度。

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