Glucose intolerance and aging: evidence for tissue insensitivity to insulin.

Suppr

超能文献

作者信息

Defronzo R A

出版信息

Diabetes. 1979 Dec;28(12):1095-101. doi: 10.2337/diab.28.12.1095.

DOI:10.2337/diab.28.12.1095

PMID:510806

Abstract

摘要

相似文献

Glucose intolerance and aging: evidence for tissue insensitivity to insulin.

Diabetes. 1979 Dec;28(12):1095-101. doi: 10.2337/diab.28.12.1095.

Serum insulin in obesity and diabetes mellitus.

Am J Clin Nutr. 1968 Dec;21(12):1419-28. doi: 10.1093/ajcn/21.12.1419.

The effect of hyperglycemia, hyperinsulinemia, and route of glucose administration on glucose oxidation and glucose storage.

Metabolism. 1982 Sep;31(9):922-30. doi: 10.1016/0026-0495(82)90183-4.

Effect of hyperglycemia per se on glucose disposal and clearance in noninsulin-dependent diabetics.

J Clin Endocrinol Metab. 1983 Apr;56(4):819-23. doi: 10.1210/jcem-56-4-819.

Glucose intolerance in uremia: site and mechanism.

Am J Clin Nutr. 1980 Jul;33(7):1438-45. doi: 10.1093/ajcn/33.7.1438.

Glucose disposal in low-birth-weight infants during steady-state hyperglycemia: effects of exogenous insulin administration.

Pediatrics. 1978 Apr;61(4):546-9.

Analysis of early-phase insulin responses in nonobese subjects with mild glucose intolerance.

Diabetes Care. 1992 Nov;15(11):1517-21. doi: 10.2337/diacare.15.11.1517.

Model for the investigation of intractable hypoglycemia: insulin-glucose interrelationships during steady state infusions.

Pediatrics. 1968 Jan;41(1):91-105.

Differential effects of hyperglycemia and hyperinsulinemia on leucine rate of appearance in normal humans.

J Clin Endocrinol Metab. 1993 Jan;76(1):203-6. doi: 10.1210/jcem.76.1.8093620.

Potentiation of insulin secretory responses by plasma glucose levels in man: evidence that hyperglycemia in diabetes compensates for imparied glucose potentiation.

J Clin Endocrinol Metab. 1979 Jun;48(6):946-54. doi: 10.1210/jcem-48-6-946.

引用本文的文献

A pilot study evaluating differences in muscle tissue saturation and blood flow between older adults with and without sarcopenia.

Front Endocrinol (Lausanne). 2025 Aug 13;16:1644712. doi: 10.3389/fendo.2025.1644712. eCollection 2025.

Transcriptomic and epigenomic signatures of liver metabolism and insulin sensitivity in aging mice.

Mech Ageing Dev. 2025 Jun;225:112068. doi: 10.1016/j.mad.2025.112068. Epub 2025 May 3.

Biomedicines. 2025 Feb 6;13(2):380. doi: 10.3390/biomedicines13020380.

Aging delays the suppression of lipolysis and fatty acid oxidation in the postprandial period.

J Appl Physiol (1985). 2024 Nov 1;137(5):1200-1219. doi: 10.1152/japplphysiol.00437.2024. Epub 2024 Sep 5.

Decreased β-cell volume and insulin secretion but preserved glucose tolerance in a growth hormone insensitive pig model.

Pituitary. 2024 Oct;27(5):567-576. doi: 10.1007/s11102-024-01424-w. Epub 2024 Jul 3.

Caloric restriction mitigates age-associated senescence characteristics in subcutaneous adipose tissue-derived stem cells.

Aging (Albany NY). 2024 May 9;16(9):7535-7552. doi: 10.18632/aging.205812.

Ultra-processed food intake, gut microbiome, and glucose homeostasis in mid-life adults: Background, design, and methods of a controlled feeding trial.

Contemp Clin Trials. 2024 Feb;137:107427. doi: 10.1016/j.cct.2024.107427. Epub 2024 Jan 4.

Glycemic and metabolic sub-classification of prediabetes and risk factors for cardiovascular disease in the D2d cohort.

Am J Prev Cardiol. 2023 Jul 27;15:100525. doi: 10.1016/j.ajpc.2023.100525. eCollection 2023 Sep.

Nicotinamide Riboside Improves Stemness of Human Adipose-Derived Stem Cells and Inhibits Terminal Adipocyte Differentiation.

Pharmaceuticals (Basel). 2023 Aug 10;16(8):1134. doi: 10.3390/ph16081134.

Methods for estimating insulin resistance from untargeted metabolomics data.

Metabolomics. 2023 Aug 9;19(8):72. doi: 10.1007/s11306-023-02035-5.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验