肠分泌：肽类的刺激作用。

Intestinal secretion: stimulation by peptides.

作者信息

Barbezat G O, Grossman M I

出版信息

Science. 1971 Oct 22;174(4007):422-4. doi: 10.1126/science.174.4007.422.

DOI:10.1126/science.174.4007.422

PMID:5111998

Abstract

Two peptides isolated from intestinal mucosa, vasoactive intestinal peptide, and gastric inhibitory peptide, stimulate small intestinal secretion in conscious dogs. Glucagon and pentagastrin also stimulate, but secretin and the octapetide of cholecystokinin do not. The stimulants may participate in regulation of intestinal secretion in health and in diseases with excessive secretion.

摘要

从肠黏膜分离出的两种肽，即血管活性肠肽和胃抑制肽，可刺激清醒犬的小肠分泌。胰高血糖素和五肽胃泌素也有刺激作用，但促胰液素和胆囊收缩素八肽则无此作用。这些刺激物可能参与健康状态以及分泌过多疾病时肠分泌的调节。