Evans D M, Cleary B K
Invest Cell Pathol. 1979 Apr-Jun;2(2):97-117.
A histological mapping procedure was used to study 32 stomachs bearing small cancers and 23 stomachs bearing ulcers. Over 80 per cent of gastric cancers and peptic ulcers occurred within 2 cm of both a mucosal junction and the lesser curvature. They showed slight differences in their longitudinal relationship to the pyloric junction. There were differential characteristics between the groups of cancers arising at each of the three mucosal junctions. Cancers at the pylorus and cardia were more common in males (M:F--2.6:1) and were predominantly well differentiated, whereas those from the intermediate zone were more common in females (M:F--1:1.8) with a relatively higher proportion of undifferentiated cancers. These and other features suggest that gastric cancers should be subdivided according to the junction of origin.
采用组织学定位程序研究了32例患有小癌的胃和23例患有溃疡的胃。超过80%的胃癌和消化性溃疡发生在黏膜交界处和胃小弯2厘米范围内。它们在与幽门交界处的纵向关系上存在细微差异。在三个黏膜交界处发生的癌组之间存在差异特征。幽门和贲门处的癌在男性中更常见（男:女——2.6:1），且主要为高分化，而来自中间区的癌在女性中更常见（男:女——1:1.8），未分化癌的比例相对较高。这些以及其他特征表明，胃癌应根据起源交界处进行细分。
