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苯巴比妥用于新生儿黄疸。

Phenobarbitone in neonatal jaundice.

作者信息

Sinniah D, Tay L K, Dugdale A E

出版信息

Arch Dis Child. 1971 Oct;46(249):712-5. doi: 10.1136/adc.46.249.712.

Abstract

Eighty-three jaundiced newborn infants were studied, 41 received phenobarbitone, and 42 served as controls. 48 hours after starting treatment the mean serum bilirubin level of the group of birthweight infants was significantly lower than that of controls. Exchange transfusions were required in 6 of the 32 control cases and in none of the 28 treated cases. There were no significant differences in the mean serum bilirubin levels or in the exchange transfusion rates between treated and control birthweight infants.

摘要

对83名黄疸新生儿进行了研究,41名接受苯巴比妥治疗,42名作为对照。开始治疗48小时后,低体重儿组的平均血清胆红素水平显著低于对照组。32名对照病例中有6名需要进行换血治疗,而28名治疗病例中无一例需要。治疗组和对照组的低体重儿在平均血清胆红素水平或换血治疗率方面没有显著差异。

相似文献

1
Phenobarbitone in neonatal jaundice.苯巴比妥用于新生儿黄疸。
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Phenobarbitone and neonatal jaundice.苯巴比妥与新生儿黄疸
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Arch Dis Child. 1974 Mar;49(3):247. doi: 10.1136/adc.49.3.247.

本文引用的文献

3
Barbiturate enhancement of bilirubin conjugation and excretion in young and adult animals.
Pediatr Res. 1968 Sep;2(5):361-70. doi: 10.1203/00006450-196809000-00005.
5
Neonatal hyperbilirubinaemia.
Med J Malaya. 1971 Mar;25(3):211-4.
6
Phenobarbitone therapy in neonatal hyperbilirubinaemia.苯巴比妥治疗新生儿高胆红素血症。
Lancet. 1969 Jul 19;2(7612):135-9. doi: 10.1016/s0140-6736(69)92443-x.
7
Controlled trials of phenobarbitone therapy of neonatal jaundice.
Lancet. 1969 May 10;1(7602):966-8. doi: 10.1016/s0140-6736(69)91862-5.
9
Phenobarbitone and neonatal jaundice.苯巴比妥与新生儿黄疸
Lancet. 1968 Nov 2;2(7575):978-9. doi: 10.1016/s0140-6736(68)91215-4.

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