Davies A J, Strachan C J, Hurlow R A, Stuart J
J Clin Pathol. 1979 Aug;32(8):822-5. doi: 10.1136/jcp.32.8.822.
A non-invasive method has been developed for the study of tissue surface fibrinolytic activity during surgery in man. Surface exudate was collected using a filter-paper disc which was then applied directly to a fibrin plate or used to prepare a euglobulin fraction. The method detected the intraoperative increase in fibrinolytic activity. At 45 minutes from the start of surgery the increase in lytic activity for tissues was four to eight times greater than that of venous blood taken simultaneously. The technique may be used to compare regional differences in tissue fibrinolysis, to determine the effect of excess local fibrinolysis on postoperative bleeding, and to study the relation between low fibrinolytic activity and postoperative adhesion formation.
已开发出一种用于研究人体手术期间组织表面纤维蛋白溶解活性的非侵入性方法。使用滤纸圆盘收集表面渗出物，然后将其直接应用于纤维蛋白平板或用于制备优球蛋白组分。该方法检测到术中纤维蛋白溶解活性增加。手术开始45分钟时，组织的溶解活性增加比同时采集的静脉血大四至八倍。该技术可用于比较组织纤维蛋白溶解的区域差异，确定局部纤维蛋白溶解过度对术后出血的影响，以及研究低纤维蛋白溶解活性与术后粘连形成之间的关系。
