Redmond W J, Rahbari H
J Am Acad Dermatol. 1979 Nov;1(5):431-6. doi: 10.1016/s0190-9622(79)70035-1.
The clinical course of ninety patients with the histopathologic diagnosis of mycosis fungoides is reviewed. An attempt is made to correlate sex, age, of onset, lesion type, and form of therapy with outcome of the disease. The data indicate that mycosis fungoides affects predominantly middle-aged males. Patients developing tumors or erythroderma in middle age or later tend to have a shorter survival. More aggressive therapy is associated with shortened survival. Most deaths were due to unknown or unrelated processes and therapeutic complications. The data support the theory that mycosis fungoides can be a relatively nonaggressive cutaneous lymphoma. In an attempt to treat aggressively, we may be exposing patients to increased mortality.
回顾了90例经组织病理学诊断为蕈样肉芽肿患者的临床病程。试图将性别、发病年龄、病变类型和治疗方式与疾病转归相关联。数据表明，蕈样肉芽肿主要影响中年男性。中年及以后出现肿瘤或红皮病的患者往往生存期较短。更积极的治疗与生存期缩短相关。大多数死亡是由于不明或不相关的过程以及治疗并发症。这些数据支持了蕈样肉芽肿可能是一种相对不具侵袭性的皮肤淋巴瘤的理论。为了进行积极治疗，我们可能会使患者面临更高的死亡率。
