Lisman J E, Brown J E
J Gen Physiol. 1971 Nov;58(5):544-61. doi: 10.1085/jgp.58.5.544.
The dark-adapted current-voltage (I-V) curve of a ventral photoreceptor cell of Limulus, measured by a voltage-clamp technique, has a high slope-resistance region more negative than resting voltage, a lower slope-resistance region between resting voltage and zero, and a negative slope-resistance region more positive than 0 v. With illumination, we find no unique voltage at which there is no light-induced current. At the termination of illumination, the I-V curve changes quickly, then recovers very slowly to a dark-adapted configuration. The voltage-clamp currents during and after illumination can be interpreted to arise from two separate processes. One process (fast) changes quickly with change in illumination, has a reversal potential at +20 mv, and has an I-V curve with positive slope resistance at all voltages. These properties are consistent with a light-induced change in membrane conductance to sodium ions. The other process (slow) changes slowly with changes in illumination, generates light-activated current at +20 mv, and has an I-V curve with a large region of negative slope resistance. The mechanism of this process cannot as yet be identified.
通过电压钳技术测量的鲎腹侧感光细胞的暗适应电流-电压（I-V）曲线，在比静息电压更负的区域有一个高斜率电阻区，在静息电压和零之间有一个较低斜率电阻区，在高于0V的区域有一个负斜率电阻区。在光照下，我们没有发现不存在光诱导电流的唯一电压。在光照终止时，I-V曲线迅速变化，然后非常缓慢地恢复到暗适应状态。光照期间和之后的电压钳电流可以解释为由两个独立的过程产生。一个过程（快速）随光照变化迅速改变，在+20mV处有一个反转电位，并且在所有电压下都有一个正斜率电阻的I-V曲线。这些特性与光诱导的膜对钠离子电导的变化一致。另一个过程（缓慢）随光照变化缓慢改变，在+20mV处产生光激活电流，并且有一个具有大的负斜率电阻区域的I-V曲线。这个过程的机制目前还无法确定。
