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Clinical progression of ocular syphilis and neurosyphilis despite treatment with massive doses of penicillin. Failure to demonstrate treponemes in affected tissues.

作者信息

Sowmini C N

出版信息

Br J Vener Dis. 1971 Oct;47(5):348-55. doi: 10.1136/sti.47.5.348.

DOI:10.1136/sti.47.5.348
PMID:5123624
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1048223/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/1f14ad2816bd/brjvendis00083-0040-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/c6785ce3e1c0/brjvendis00083-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/605ed1b90ecc/brjvendis00083-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/f80961a392af/brjvendis00083-0035-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/38a04215528e/brjvendis00083-0035-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/8d7108eb71cb/brjvendis00083-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/3de1574ddc06/brjvendis00083-0036-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/47cb5f6c2cf0/brjvendis00083-0036-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/deb2c00a0683/brjvendis00083-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/285d543c377a/brjvendis00083-0037-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/891c94dbcc63/brjvendis00083-0037-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/2e6eda6f217b/brjvendis00083-0037-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/3763d4107dc4/brjvendis00083-0038-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/7787cac3fddf/brjvendis00083-0039-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/3d0761d272d1/brjvendis00083-0039-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/80356cb48ec8/brjvendis00083-0040-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/1f14ad2816bd/brjvendis00083-0040-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/c6785ce3e1c0/brjvendis00083-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/605ed1b90ecc/brjvendis00083-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/f80961a392af/brjvendis00083-0035-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/38a04215528e/brjvendis00083-0035-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/8d7108eb71cb/brjvendis00083-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/3de1574ddc06/brjvendis00083-0036-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/47cb5f6c2cf0/brjvendis00083-0036-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/deb2c00a0683/brjvendis00083-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/285d543c377a/brjvendis00083-0037-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/891c94dbcc63/brjvendis00083-0037-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/2e6eda6f217b/brjvendis00083-0037-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/3763d4107dc4/brjvendis00083-0038-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/7787cac3fddf/brjvendis00083-0039-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/3d0761d272d1/brjvendis00083-0039-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/80356cb48ec8/brjvendis00083-0040-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/1048223/1f14ad2816bd/brjvendis00083-0040-b.jpg

相似文献

1
Clinical progression of ocular syphilis and neurosyphilis despite treatment with massive doses of penicillin. Failure to demonstrate treponemes in affected tissues.尽管使用大剂量青霉素治疗，眼梅毒和神经梅毒仍出现临床进展。在受影响组织中未检测到梅毒螺旋体。
Br J Vener Dis. 1971 Oct;47(5):348-55. doi: 10.1136/sti.47.5.348.
2
Late ocular syphilis: transfer of infection from man to experimental animals.晚期眼梅毒：感染从人向实验动物的传播。
Trans Am Ophthalmol Soc. 1969;67:658-97.
3
The treatment of syphilis.梅毒的治疗。
Surv Ophthalmol. 1969 Nov;14(3):184-97.
4
Demonstration of treponeme-like forms in cases of treated and untreated late syphilis and of treated early syphilis.在已治疗和未治疗的晚期梅毒病例以及已治疗的早期梅毒病例中发现类梅毒螺旋体形态。
Br J Vener Dis. 1970 Feb;46(1):1-9. doi: 10.1136/sti.46.1.1.
5
Symptoms 20 years after treatment of secondary syphilis.二期梅毒治疗20年后的症状。
JAMA. 1969 Feb 3;207(5):961. doi: 10.1001/jama.207.5.961c.
6
Intraocular treponemes.
Arch Ophthalmol. 1968 Sep;80(3):303-7. doi: 10.1001/archopht.1968.00980050305002.
7
Whither late ocular and neurosyphilis?晚期眼梅毒和神经梅毒何去何从？
J Clin Neuroophthalmol. 1982 Jun;2(2):75-6.
8
Neurosyphilis in Brazilian newborns: a health problem that could be avoided.巴西新生儿中的神经梅毒：一个可以避免的健康问题。
Rev Inst Med Trop Sao Paulo. 2020 Nov 9;62:e82. doi: 10.1590/S1678-9946202062082. eCollection 2020.
9
Ocular syphilis and neurosyphilis in a patient with human immunodeficiency virus infection.一名感染人类免疫缺陷病毒的患者出现眼梅毒和神经梅毒。
Md Med J. 1995 Apr;44(4):284-8.
10
Asymptomatic neurosyphilis after doxycycline therapy for early latent syphilis.
Sex Transm Dis. 1993 Nov-Dec;20(6):346-7.

本文引用的文献

1
TREPONEMAL SURVIVAL IN HUMANS AFTER PENICILLIN THERAPY: A PRELIMINARY REPORT.青霉素治疗后梅毒螺旋体在人体内的存活情况：初步报告。
Br J Vener Dis. 1964 Dec;40(4):248-53. doi: 10.1136/sti.40.4.248.
2
[Study of the effect of penicillin in late syphilis: persistence of Treponema pallidum following treatment. 1. Late syphilis--expeimental].[青霉素治疗晚期梅毒的效果研究：治疗后梅毒螺旋体的持续存在。1. 晚期梅毒——实验性研究]
Ann Inst Pasteur (Paris). 1962 May;102:596-615.