营养不良儿童的肠道二肽水解酶活性
Intestinal dipeptide hydrolase activities in undernourished children.
作者信息
Kumar V, Ghai O P, Chase H P
出版信息
Arch Dis Child. 1971 Dec;46(250):801-4. doi: 10.1136/adc.46.250.801.
Abstract
Intestinal dipeptide hydrolase enzymes cleave dipeptides into amino acids. In 8 undernourished children with diarrhoea, mean intestinal mucosal glyclyl-proline hydrolase activity was reduced 40%, valyl-proline hydrolase activity 38%, and alkaline phosphatase activity 54%, as compared with 4 controls. The use of hydrolysed proteins or simple amino acid mixtures in the initial treatment of undernourished children is suggested.
摘要
肠道二肽水解酶可将二肽裂解为氨基酸。与4名对照儿童相比，8名营养不良腹泻儿童的肠道黏膜甘氨酰脯氨酸水解酶活性平均降低了40%，缬氨酰脯氨酸水解酶活性降低了38%，碱性磷酸酶活性降低了54%。建议在营养不良儿童的初始治疗中使用水解蛋白或简单氨基酸混合物。
相似文献
1
Intestinal dipeptide hydrolase activities in undernourished children.营养不良儿童的肠道二肽水解酶活性
Arch Dis Child. 1971 Dec;46(250):801-4. doi: 10.1136/adc.46.250.801.
2
Undernutrition and intestinal dipeptide hydrolase activity in the rat.大鼠的营养不良与肠道二肽水解酶活性
J Nutr. 1971 Nov;101(11):1509-14. doi: 10.1093/jn/101.11.1509.
3
Dipeptide hydrolase activity of the intestinal mucosa from protein-malnourished adult patients and controls.蛋白质营养不良成年患者及对照者肠黏膜的二肽水解酶活性
Am J Clin Nutr. 1977 Jul;30(7):1044-53. doi: 10.1093/ajcn/30.7.1044.
4
Progressive protein undernutrition and intestinal enzyme activities in monkeys.猴子体内进行性蛋白质营养不良与肠道酶活性
Am J Clin Nutr. 1972 May;25(5):485-9. doi: 10.1093/ajcn/25.5.485.
5
Multiple forms of dipeptidases in normal human intestinal mucosa and in mucosa from children with coeliac disease.
Clin Chim Acta. 1969 Dec;26(3):555-8. doi: 10.1016/0009-8981(69)90087-4.
6
[Enzyme activity of the mucous membrane of the small intestine in growing rats under the chronic influence of high temperatures].[高温长期影响下生长中大鼠小肠黏膜的酶活性]
Biull Eksp Biol Med. 1973 Jun;75(6):21-3.
7
Intestinal dipeptidases in primary protein malnutrition.原发性蛋白质营养不良中的肠道二肽酶
Am J Clin Nutr. 1974 Jul;27(7):760-3. doi: 10.1093/ajcn/27.7.760.
8
Studies on intestinal hydrolysis of peptides. I. L-glutaminyl-L-proline dipeptide hydrolase activity in the human small intestine.
Biochim Biophys Acta. 1969;191(3):663-7. doi: 10.1016/0005-2744(69)90359-3.
9
Abnormalities of jejunal mucosal enzymes in ulcerative colitis and Crohn's disease.溃疡性结肠炎和克罗恩病患者空肠黏膜酶异常。
Digestion. 1979;19(4):259-66. doi: 10.1159/000198354.
10
Subcellular fractionation of the enterocyte with special reference to peptide hydrolases.肠细胞的亚细胞分级分离，特别涉及肽水解酶。
Ciba Found Symp. 1971:107-22. doi: 10.1002/9780470719879.ch8.
引用本文的文献
1
Study of enzyme activities in the descending part of the duodenum in patients of duodenal ulcer.十二指肠溃疡患者十二指肠降部酶活性的研究。
Indian J Clin Biochem. 2006 Mar;21(1):169-72. doi: 10.1007/BF02913089.
2
Biochemistry of protein-calorie malnutrition. A review of some recent advances.蛋白质-热量营养不良的生物化学。近期一些进展的综述。
Indian J Pediatr. 1975 May;42(328):128-32. doi: 10.1007/BF02796483.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The effect of protein hydrolysate on initiation of cure and various biochemical indices of recovery in kwashiorkor.蛋白质水解物对夸希奥科病治愈起始及恢复过程中各项生化指标的影响。
S Afr J Lab Clin Med. 1961 Sep;7:108-13.
3
ACQUIRED DISACCHARIDE INTOLERANCE IN MALNUTRITION.营养不良中的后天性双糖不耐受
J Pediatr. 1965 Jun;66:1083-91. doi: 10.1016/s0022-3476(65)80095-6.
4
FAT ABSORPTION STUDIES IN MALNOURISHED CHILDREN.营养不良儿童的脂肪吸收研究。
Am J Clin Nutr. 1964 Nov;15:287-92. doi: 10.1093/ajcn/15.5.287.
5
A SIMPLIFIED GASTROINTESTINAL BIOPSY CAPSULE.一种简化的胃肠道活检胶囊。
Gastroenterology. 1964 May;46:550-7.
6
7
Protein-calorie malnutrition: effect of deficient diets on enzyme levels of jejunal mucosa of rats.蛋白质 - 热量营养不良：缺乏营养的饮食对大鼠空肠黏膜酶水平的影响。
Br J Nutr. 1967;21(1):55-68. doi: 10.1079/bjn19670009.
8
Carbohydrate absorption in malnourished children.
Am J Clin Nutr. 1967 Feb;20(2):89-97. doi: 10.1093/ajcn/20.2.89.
9
Intestinal dipeptidases. Dipeptidase activity in the mucosa of the gastrointestinal tract of the adult human.肠二肽酶。成年人类胃肠道黏膜中的二肽酶活性。
Acta Physiol Scand. 1966 Apr;66(4):437-43. doi: 10.1111/j.1748-1716.1966.tb03221.x.
10
Intestinal dipeptidases. I. Spectrophotometric determination and characterization of dipeptidase activity in pig intestinal mucosa.肠二肽酶。I. 猪肠黏膜中二肽酶活性的分光光度法测定及特性研究
Biochim Biophys Acta. 1965 Jul 29;105(1):149-61. doi: 10.1016/s0926-6593(65)80183-7.
Zotero 插件