传染性单核细胞增多症的血小板缺陷
Platelet defect of infectious mononucleosis.
作者信息
Clancy R, Jenkins E, Firkin B
出版信息
Br Med J. 1971 Dec 11;4(5788):646-8. doi: 10.1136/bmj.4.5788.646.
Abstract
Platelet function has been studied in 16 patients with uncomplicated infectious mononucleosis. Some abnormality of platelet aggregation and/or release of platelet factor III or platelet factor IV was found in all patients. Six patients with platelet defects were retested after three to four months and were found to have normal platelet function and appreciably higher platelet counts. Abnormal platelet function may reflect a platelet defect which predisposes to premature platelet destruction. Recent viral illness should be excluded before attributing abnormal platelet function to other factors or to a congenital disorder.
摘要
对16例无并发症的传染性单核细胞增多症患者的血小板功能进行了研究。所有患者均发现血小板聚集和/或血小板因子III或血小板因子IV释放存在某种异常。6例有血小板缺陷的患者在三到四个月后重新进行检测，发现血小板功能正常且血小板计数明显更高。血小板功能异常可能反映了一种易于导致血小板过早破坏的血小板缺陷。在将血小板功能异常归因于其他因素或先天性疾病之前，应排除近期的病毒感染。
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