Gunstone R F, Wing A J, Shani H G, Njemo D, Sabuka E M
Postgrad Med J. 1971 Dec;47(554):789-93. doi: 10.1136/pgmj.47.554.789.
The use of metolazone (Zaroxolyn), a new diuretic, in fifty-two African patients is described. The drug was found to be safe and moderately effective when used alone, but combined with frusemide it proved to be of great value in patients whose fluid retention was refractory to other diuretics.
本文描述了一种新型利尿剂美托拉宗(Zaroxolyn)在52例非洲患者中的使用情况。结果发现,该药物单独使用时安全且有一定疗效,但与速尿联合使用时,对于其他利尿剂治疗无效的液体潴留患者具有重要价值。