伴刀豆球蛋白A刺激的淋巴细胞在体外对靶细胞的破坏作用。
Target cell destruction in vitro by concanavalin A-stimulated lymphoid cells.
作者信息
Schwartz H J, Wilson F
出版信息
Am J Pathol. 1971 Aug;64(2):295-304.
Abstract
Guinea pig lymphoid cells obtained from lymph nodes and spleens of nonimmune animals are cytotoxic for mouse L-cell fibroblasts on incubation with concanavalin A. This effect is blocked by methyl-alpha-D-mannoside. The results indicate that this effect may be due to the release of a lymphotoxin by the concanavalin A-stimulated lymphocytes.
摘要
从非免疫动物的淋巴结和脾脏获得的豚鼠淋巴细胞，在与伴刀豆球蛋白A孵育时，对小鼠L细胞成纤维细胞具有细胞毒性。这种效应被α-D-甲基甘露糖苷阻断。结果表明，这种效应可能是由于伴刀豆球蛋白A刺激的淋巴细胞释放了一种淋巴毒素。
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