Valeev A E, Dzhakhangirov F N, Magura I S, Sadritdinov F S
Neirofiziologiia. 1979;11(5):469-74.
The effect of alkoloid lappaconitine on ionic currents through the somatic membrane of identified neurons of the mollusc Helix pomatia was studied under voltage-clamp conditions. It is shown that 4 mM lappaconitine causes a reversible blocking action on the calcium channels. Concentration exceeding 4 mM causes irreversible changes. Lappaconitine had either an insignificant or no effect on sodium currents.
在电压钳条件下，研究了生物碱拉帕乌头碱对软体动物皱襞螺已鉴定神经元体膜离子电流的影响。结果表明，4 mM拉帕乌头碱对钙通道产生可逆性阻断作用。浓度超过4 mM会导致不可逆变化。拉帕乌头碱对钠电流的影响不显著或无影响。
