[Effect of the alkaloid lappaconitine on ion currents through the somatic membrane of Helix pomatia neurons].

The effect of alkoloid lappaconitine on ionic currents through the somatic membrane of identified neurons of the mollusc Helix pomatia was studied under voltage-clamp conditions. It is shown that 4 mM lappaconitine causes a reversible blocking action on the calcium channels. Concentration exceeding 4 mM causes irreversible changes. Lappaconitine had either an insignificant or no effect on sodium currents.