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一名男性患者出现性染色质阳性转移性黑色素瘤，预后良好。

Sex chromatin positive metastatic melanoma in a male with a favourable prognosis.

作者信息

Atkin N B

出版信息

Br J Cancer. 1971 Sep;25(3):487-92. doi: 10.1038/bjc.1971.61.

DOI:10.1038/bjc.1971.61
PMID:5144523
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2008744/
Abstract

The presence of sex chromatin in a metastatic malignant melanoma from a male patient aged 26 who showed no evidence of any constitutional chromosome anomaly is described. A possible association between the apparently "female" origin of the tumour and the good response to therapy is considered.

摘要

本文描述了一名26岁男性转移性恶性黑色素瘤患者体内存在性染色质的情况，该患者未发现任何先天性染色体异常的迹象。文中还探讨了肿瘤明显的“女性”起源与对治疗的良好反应之间可能存在的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/54e014b54066/brjcancer00360-0139-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/802ed0b7826b/brjcancer00360-0136-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/33c7eaca4d51/brjcancer00360-0137-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/0354afa9cca8/brjcancer00360-0140-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/81ab4de17361/brjcancer00360-0138-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/b4460e5a6725/brjcancer00360-0135-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/54e014b54066/brjcancer00360-0139-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/802ed0b7826b/brjcancer00360-0136-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/33c7eaca4d51/brjcancer00360-0137-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/0354afa9cca8/brjcancer00360-0140-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/81ab4de17361/brjcancer00360-0138-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/b4460e5a6725/brjcancer00360-0135-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca1f/2008744/54e014b54066/brjcancer00360-0139-a.jpg

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1
Sex chromatin positive metastatic melanoma in a male with a favourable prognosis.一名男性患者出现性染色质阳性转移性黑色素瘤，预后良好。
Br J Cancer. 1971 Sep;25(3):487-92. doi: 10.1038/bjc.1971.61.
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本文引用的文献

1
METASTATIC MALIGNANT MELANOMA FROM MOTHER TO FETUS.
Cancer. 1965 Aug;18:1048-54. doi: 10.1002/1097-0142(196508)18:8<1048::aid-cncr2820180817>3.0.co;2-v.
2
Chromosomes of human cancer cells.人类癌细胞的染色体。
Br Med J. 1962 Dec 1;2(5317):1431-5. doi: 10.1136/bmj.2.5317.1431.
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Melanoma in twins. Cutaneous malignant melanoma in identical twins from a set of triplets.双胞胎中的黑色素瘤。一组三胞胎中同卵双胞胎的皮肤恶性黑色素瘤。
Cancer. 1970 Mar;25(3):672-7. doi: 10.1002/1097-0142(197003)25:3<672::aid-cncr2820250324>3.0.co;2-a.
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Polyploidy in malignant melanoma.恶性黑色素瘤中的多倍体现象。
Cancer. 1970 May;25(5):1216-23. doi: 10.1002/1097-0142(197005)25:5<1216::aid-cncr2820250529>3.0.co;2-x.
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[Studies on the familial incidence of skin melanoma].[皮肤黑色素瘤的家族发病率研究]
Tumori. 1969 May-Jun;55(3):161-6.
6
Chromosome analysis of solid tumors. I. Twenty-eight nonepithelial tumors.实体瘤的染色体分析。I. 28例非上皮性肿瘤。
Cancer. 1967 Aug;20(8):1253-73. doi: 10.1002/1097-0142(196708)20:8<1253::aid-cncr2820200810>3.0.co;2-8.
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Human malignant melanoma antibodies demonstrated by immunofluorescence.通过免疫荧光法显示的人类恶性黑色素瘤抗体。
Arch Surg. 1970 Apr;100(4):491-7. doi: 10.1001/archsurg.1970.01340220167028.
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Tumour-specific antibodies in human malignant melanoma and their relationship to the extent of the disease.人类恶性黑色素瘤中的肿瘤特异性抗体及其与疾病程度的关系。
Br Med J. 1969 Sep 6;3(5670):547-52. doi: 10.1136/bmj.3.5670.547.
9
Cutaneous hypersensitivity reactions to autologous extracts of malignant melanoma cells.
Lancet. 1970 Jan 17;1(7638):116-8. doi: 10.1016/s0140-6736(70)90467-8.