乳腺癌预后因素的相对重要性。
The relative significance of prognostic factors in breast carcinoma.
作者信息
Alderson M R, Hamlin I, Staunton M D
出版信息
Br J Cancer. 1971 Dec;25(4):646-56. doi: 10.1038/bjc.1971.80.
Abstract
A retrospective detailed study of 272 cases of breast carcinoma treated by radical mastectomy was published by Hamlin (1968). An extended analysis of the material for 258 of these cases is now reported.Data for 21 prognostic factors from 258 patients have been subjected to multiple regression analysis to determine the independent effect and thus the relative importance of each factor. The findings confirm previous single factor analyses and demonstrate that nine of the factors are independently associated with survival.Mathematical manipulation of the information obtained in this analysis allowed a risk score to be allotted to each patient. Grouping of patients by the prediction scores is found in this series to be more closely related to survival than is clinical staging of the same patients.
摘要
哈姆林（1968年）发表了一项对272例接受根治性乳房切除术治疗的乳腺癌病例的回顾性详细研究。现报告对其中258例病例资料的进一步分析。对258例患者的21个预后因素数据进行了多元回归分析，以确定各因素的独立作用，从而确定每个因素的相对重要性。研究结果证实了先前的单因素分析，并表明其中9个因素与生存率独立相关。对该分析中获得的信息进行数学处理，可为每位患者分配一个风险评分。在本系列研究中发现，根据预测评分对患者进行分组与生存率的相关性比相同患者的临床分期更为密切。
相似文献
1
The relative significance of prognostic factors in breast carcinoma.乳腺癌预后因素的相对重要性。
Br J Cancer. 1971 Dec;25(4):646-56. doi: 10.1038/bjc.1971.80.
2
An analysis of clinical and histopathological features in 101 cases of carcinoma of breast in women under 35 years of age.101例35岁以下女性乳腺癌患者的临床及组织病理学特征分析。
Br J Cancer. 1970 Dec;24(4):644-69. doi: 10.1038/bjc.1970.78.
3
[Extended radical mastectomy for cancer: statistical analysis made with electronic computers of the prognostic significance of some clinical data and of the presence of regional lymph node metastases at the operation].[乳腺癌扩大根治术：利用电子计算机对某些临床数据的预后意义以及手术时区域淋巴结转移情况进行的统计分析]
Policlinico Prat. 1970 Jun;77(25):807-15.
4
The tumor-to-breast volume ratio (TBR) predicts cancer-specific survival in breast cancer patients who underwent modified radical mastectomy.肿瘤与乳房体积比（TBR）可预测接受改良根治性乳房切除术的乳腺癌患者的癌症特异性生存率。
Tumour Biol. 2016 Jun;37(6):7493-500. doi: 10.1007/s13277-015-4382-2. Epub 2015 Dec 17.
5
Women treated with breast conserving surgery do better than those with mastectomy independent of detection mode, prognostic and predictive tumor characteristics.接受保乳手术治疗的女性比接受乳房切除术的女性情况更好，这与检测方式、肿瘤的预后和预测特征无关。
Eur J Surg Oncol. 2015 Oct;41(10):1417-22. doi: 10.1016/j.ejso.2015.07.002. Epub 2015 Jul 17.
6
Significance of local recurrence as a prognostic factor in the treatment of breast cancer.局部复发作为乳腺癌治疗中一个预后因素的意义。
Anticancer Res. 2006 Jan-Feb;26(1B):569-73.
7
[Oncological safety and prognosis factors analysis of immediate breast reconstruction after nipple-areola-complex sparing mastectomy].[保留乳头乳晕复合体的乳房切除术后即刻乳房重建的肿瘤学安全性及预后因素分析]
Zhonghua Zhong Liu Za Zhi. 2018 Sep 23;40(9):690-695. doi: 10.3760/cma.j.issn.0253-3766.2018.09.011.
8
[Breast-conservation treatment for early invasive breast cancer: prognostic factors for survival after salvage treatment of local recurrence].[早期浸润性乳腺癌的保乳治疗：局部复发挽救治疗后生存的预后因素]
Magy Onkol. 2007;51(2):127-31. Epub 2007 Jul 29.
9
"Clinical significance of multifocal and multicentric breast cancers and choice of surgical treatment: a retrospective study on a series of 1158 cases".多灶性和多中心性乳腺癌的临床意义及手术治疗选择：对1158例病例的回顾性研究
BMC Surg. 2015 Jan 14;15(1):1. doi: 10.1186/1471-2482-15-1.
10
[Evidence-based radiotherapy in the treatment of early-stage invasive breast cancer: traditional clinical features and biomarkers].[早期浸润性乳腺癌治疗中的循证放疗：传统临床特征与生物标志物]
Magy Onkol. 2009 Mar;53(1):7-14. doi: 10.1556/MOnkol.53.2009.1.2.
引用本文的文献
1
The specific shapes of capillaries are associated with worse prognosis in patients with invasive breast cancer.毛细血管的特定形态与浸润性乳腺癌患者的预后较差有关。
Pathol Int. 2024 Jul;74(7):394-407. doi: 10.1111/pin.13442. Epub 2024 May 31.
2
Artificial Intelligence Helps Pathologists Increase Diagnostic Accuracy and Efficiency in the Detection of Breast Cancer Lymph Node Metastases.人工智能帮助病理学家提高乳腺癌淋巴结转移检测的诊断准确性和效率。
Am J Surg Pathol. 2024 Jul 1;48(7):846-854. doi: 10.1097/PAS.0000000000002248. Epub 2024 May 27.
3
Prognostic value of poorly differentiated clusters in invasive breast cancer.浸润性乳腺癌中低分化簇的预后价值。
World J Surg Oncol. 2014 Oct 12;12:310. doi: 10.1186/1477-7819-12-310.
4
Effect on survival of longer intervals between confirmed diagnosis and treatment initiation among low-income women with breast cancer.低收入乳腺癌女性确诊后治疗启动时间间隔延长对生存的影响。
J Clin Oncol. 2012 Dec 20;30(36):4493-500. doi: 10.1200/JCO.2012.39.7695. Epub 2012 Nov 19.
5
Waiting time for breast cancer treatment in Alberta.阿尔伯塔省乳腺癌治疗的等待时间。
Can J Public Health. 2004 Sep-Oct;95(5):341-5. doi: 10.1007/BF03405142.
6
The influence on survival of delay in the presentation and treatment of symptomatic breast cancer.有症状乳腺癌的就诊和治疗延迟对生存的影响。
Br J Cancer. 1999 Feb;79(5-6):858-64. doi: 10.1038/sj.bjc.6690137.
7
Angiogenesis and inflammation in invasive carcinoma of the breast.乳腺癌浸润性癌中的血管生成与炎症
J Clin Pathol. 1997 Aug;50(8):669-73. doi: 10.1136/jcp.50.8.669.
8
Matrix metalloproteinase inhibitors in the treatment of cancer.
Med Oncol. 1997 Mar;14(1):1-10. doi: 10.1007/BF02990939.
9
Histopathology of breast cancer in relation to age.乳腺癌的组织病理学与年龄的关系。
Br J Cancer. 1997;75(4):593-6. doi: 10.1038/bjc.1997.103.
10
Inflammatory infiltrate in invasive lobular and ductal carcinoma of the breast.乳腺浸润性小叶癌和导管癌中的炎性浸润
Br J Cancer. 1996 Sep;74(5):796-801. doi: 10.1038/bjc.1996.438.
本文引用的文献
1
Natural history of untreated breast cancer (1805-1933). Comparison of untreated and treated cases according to histological grade of malignancy.未经治疗的乳腺癌的自然史（1805 - 1933年）。根据恶性组织学分级对未经治疗和经治疗的病例进行比较。
Br Med J. 1962 Jul 28;2(5299):213-21. doi: 10.1136/bmj.2.5299.213.
2
A report of 549 cases of breast cancer in women 35 years of age or younger.一份关于35岁及以下女性549例乳腺癌病例的报告。
Surg Gynecol Obstet. 1958 Sep;107(3):271-83.
3
Sinus histiocytosis of lymph nodes in cancer.癌症中的淋巴结窦组织细胞增生症
Surg Gynecol Obstet. 1958 Feb;106(2):163-75.
4
Cancer of the female breast, mortality, and the menopause.女性乳腺癌、死亡率与绝经
Lancet. 1955 Nov 26;269(6900):1129-30. doi: 10.1016/s0140-6736(55)92964-0.
5
The use of prognostic factors in predicting survival for breast cancer patients.预后因素在预测乳腺癌患者生存率中的应用。
J Chronic Dis. 1966 Aug;19(8):923-33. doi: 10.1016/0021-9681(66)90008-7.
6
Possible host resistance in carcinoma of the breast: a histological study.乳腺癌中可能存在的宿主抵抗力：一项组织学研究。
Br J Cancer. 1968 Sep;22(3):383-401. doi: 10.1038/bjc.1968.47.
7
[Prognostic value of blood cholesterol in women with cancer of the breast].[血液胆固醇对乳腺癌女性患者的预后价值]
Pathol Biol. 1967 May;15(9):515-8.
8
Further observations on prognostic factors in cancer of the female breast.
Cancer. 1969 Oct;24(4):653-67. doi: 10.1002/1097-0142(196910)24:4<653::aid-cncr2820240402>3.0.co;2-b.
Zotero 插件