Bennett E D, Smithen C S, Sowton E
Thorax. 1971 Nov;26(6):632-7. doi: 10.1136/thx.26.6.632.
Systolic time intervals were measured in 24 patients with acute myocardial infarction and compared to normal values predicted for heart rate and sex. Pulmonary artery pressures were measured in 18 patients and cardiac outputs using the Fick technique in 10 patients. In all patients the QS2 interval (total electromechanical systole) was short during the acute episode. This shortening in the QS2 interval was due primarily to a reduction in left ventricular ejection time (r=0·71; P<0·001) with no change in the pre-ejection period. The mean deviation from normal of the QS2 interval was 27 ± 3·6 msec in patients with an uncomplicated clinical course and 52 ± 4·7 msec in patients with a complicated course, the difference being significant at the 1% level. Those patients with the highest pulmonary artery diastolic pressure tended to have the shortest QS2 intervals (r=−0·58; P<0·01). There was no relationship between stroke volume and the deviations in the QS2 and left ventricular ejection time intervals from normal. The implication of these findings is discussed.
对24例急性心肌梗死患者测量了收缩期时间间期，并与根据心率和性别预测的正常值进行比较。对18例患者测量了肺动脉压，对10例患者采用菲克技术测量了心输出量。在所有患者中，急性发作期间QS2间期（总机电收缩期）缩短。QS2间期的这种缩短主要是由于左心室射血时间缩短（r = 0·71；P < 0·001），而射血前期无变化。临床过程无并发症的患者，QS2间期与正常的平均偏差为27±3·6毫秒，临床过程复杂的患者为52±4·7毫秒，两者差异在1%水平上具有显著性。肺动脉舒张压最高的患者往往QS2间期最短（r = -0·58；P < 0·01）。每搏量与QS2及左心室射血时间间期与正常的偏差之间无相关性。讨论了这些发现的意义。
