Bessot M, Mauuary G, Lorenzini G, Fays J, Colombel P, Duprez A
Sem Hop. 1975 Feb 20;51(9):601-8.
Fifty patients with a stomach cancer received regional chemotherapy by infusion. Two kinds of cancers were treated with this technique: cancers inaccessible with usual surgical treatment and some limited cancers. In most cases, the catheter was introduced by transcutaneous puncture of axillary artery. According to the site of the cancer, the extremity of the catheter was introduced into the left gastric artery, hepatic artery or coeliac trunk. Efficiency of the infusion was checked by arteriography and by gastric fibroscopic examination with intra-arterial injection of evans blue. The duration of the treatment was two weeks or three weeks. The chemotherapy was made on a sequential method, taking account of the tumoral cellular cycle. The results show an objective response in 80 per cent of the cases, 39 per cent of the non operable cancers were later accessible to surgery. This study shows that chemotherapy should be used in the treatment of any stomach's cancers before surgical treatment.
50例胃癌患者接受了区域性灌注化疗。该技术用于治疗两种类型的癌症：常规手术难以触及的癌症和一些局限性癌症。在大多数情况下，通过经皮穿刺腋动脉插入导管。根据癌症部位，将导管末端插入胃左动脉、肝动脉或腹腔干。通过动脉造影以及在动脉内注射伊文思蓝后进行胃纤维镜检查来检查灌注效果。治疗持续时间为两周或三周。化疗采用序贯方法，考虑肿瘤细胞周期。结果显示80%的病例有客观反应，39%原本无法手术的癌症后来可以进行手术。这项研究表明，在手术治疗前，化疗应用于所有胃癌的治疗。
